Evidence map›Paper›PMID 32170715›Full record

ArticleHuman cell2020

Candesartan ameliorates vascular smooth muscle cell proliferation via regulating miR-301b/STAT3 axis.

Ling Zhang, Fan Yang, Qiong Yan

Abstract read
PubMed Publisher
In one paragraph

Article in Human cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Endothelial Function Biomarkers in Hypertension.Current medicinal chemistry · 2025
    Review
  2. The pharmaco-epigenetics of hypertension: a focus on microRNA.Molecular and cellular biochemistry · 2024
    Review
  3. Article
  4. Article
  5. MiRNAs, lncRNAs, and circular RNAs as mediators in hypertension-related vascular smooth muscle cell dysfunction.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ling ZhangDepartment of Pharmacy, Xiantao First People's Hospital, No. 29 Mianzhou Road, Xiantao, 433000, Hubei, China. zhling_hbxtyy@126.com.
Fan YangDepartment of Pharmacy, Xiantao First People's Hospital, No. 29 Mianzhou Road, Xiantao, 433000, Hubei, China.
Qiong YanDepartment of Pharmacy, Huazhong University of Science and Technology Hospital, Wuhan, 430074, Hubei, China.
Huazhong University of Science and Technology Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive vascular smooth muscle cell (VSMC) proliferation contributes to vascular remodeling and stroke during hypertension. Blockade of Angiotensin (AngII) type 1 receptor (AT

Indexed as

BenzimidazolesBiphenyl CompoundsCardiovascular AgentsCell ProliferationCells, CulturedDown-RegulationGene Expression Regulation, DevelopmentalHumansMicroRNAsMuscle, Smooth, VascularSTAT3 Transcription FactorTetrazolesBenzimidazolesBiphenyl CompoundscandesartanCardiovascular AgentsMicroRNAsMIRN301A microRNA, humanSTAT3 protein, humanSTAT3 Transcription FactorTetrazolesCandesartanmiR-301bProliferationSTAT3Vascular smooth muscle cell

Identifiers

PMID32170715
OpenAlexW3011017362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.