Evidence map›Paper›PMID 32170529›Full record

ReviewHeart failure reviews2021

Comprehensive assessment of hypertensive heart disease: cardiac magnetic resonance in focus.

Marijana Tadic, Cesare Cuspidi, Sven Plein, Isidora Grozdic Milivojevic, Dao Wen Wang, Guido Grassi, Giuseppe Mancia

Abstract readReview
PubMed Publisher
In one paragraph

Review in Heart failure reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

  1. Causal atlas on comorbidities in cardiomyopathy: a Mendelian randomization study of European ancestry.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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  17. Hypertensive Heart Disease-The Imaging Perspective.Journal of clinical medicine · 2023
    Review
  18. Article
  19. Review
  20. Can myocardial work help in the therapy of resistant hypertension?Journal of clinical hypertension (Greenwich, Conn.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Marijana TadicDepartment of Cardiology, University Hospital "Dr. Dragisa Misovic - Dedinje", Heroja Milana Tepica 1, Belgrade, 11000, Serbia. marijana_tadic@hotmail.com.
Cesare CuspidiUniversity of Milan-Bicocca, Milan, Italy.
Sven PleinDepartment of Biomedical Imaging Science, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Isidora Grozdic MilivojevicCenter for Nuclear Medicine Clinical Center of Serbia, Belgrade, Serbia.
Dao Wen WangDepartment of Internal Medicine, Division of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Guido GrassiUniversity of Milan-Bicocca, Milan, Italy.
Giuseppe ManciaUniversity of Milan-Bicocca, Milan, Italy.
University of Milano-Bicocca · ITHuazhong University of Science and Technology · CNIRCCS Istituto Auxologico Italiano · ITUniversity Hospital Center Dr Dragiša Mišović · RSUniversity of Belgrade · RSUniversity of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial hypertension represents the most frequent cardiovascular risk factor that is associated with cardiac remodeling. Hypertensive heart disease was defined by the presence of left ventricular hypertrophy (LVH) and diastolic dysfunction, and it has been diagnosed by echocardiography in everyday clinical practice. Interstitial myocardial fibrosis is the underlying cause of hypertension-induced cardiac remodeling, and it could not be visualized with different echocardiographic methods. Cardiac magnetic resonance (CMR) and its methods such as late gadolinium enhancement, and T1 mapping provides qualitative and quantitative assessment of interstitial myocardial fibrosis in hypertensive patients. Furthermore, CMR can provide differentiation of LVH between hypertensive patients and cardiomyopathies (hypertrophic or Fabry disease). Timely diagnosis of cardiac impairment and early treatment is essential because regression of LVH could be achieved with adequate treatment. Diffuse cardiac fibrosis in hypertensive patients might be an underlying mechanism that explains the increased cardiovascular morbidity and mortality in this population. Future longitudinal investigations are necessary to determine causal relationship between diffuse fibrosis and cardiovascular outcome in these patients. The aim of this review is to summarize the current knowledge regarding CMR techniques and their potential usage in patients with hypertensive heart disease.

Indexed as

Heart DiseasesHypertensionContrast MediaFibrosisGadoliniumHumansHypertrophy, Left VentricularMagnetic Resonance Imaging, CineMagnetic Resonance SpectroscopyMyocardiumVentricular RemodelingContrast MediaGadoliniumCardiac magnetic resonanceLate gadolinium enhancementLeft ventricleStrainT1 mapping

Identifiers

PMID32170529
OpenAlexW3012008468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.