ArticleScientific reports2020
Risk factors of meconium-related ileus in very low birth weight infants: patients-control study.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- When It Is Not NEC: Recognizing Mimics of Necrotizing Enterocolitis in Preterm Infants.Children (Basel, Switzerland) · 2026Review
- Peritoneal drainage in spontaneous intestinal perforation: a 20-year single center review.Pediatric surgery international · 2026Article
- Meconium obstruction of prematurity in tiny babies - towards developing an international consensus.Journal of perinatology : official journal of the California Perinatal Association · 2025Review
- Doppler abnormality predisposes preterm infants with fetal growth restriction to postnatal intestinal disorder.The journal of obstetrics and gynaecology research · 2025Article
- Aggressive enema and surgery for meconium-related ileus in extremely low-birth-weight infants.Pediatric surgery international · 2025Article
- Hydrostatic low-volume enemas in infants with birth weight ≤1000 g or gestational age ≤28 weeks: A controlled interventional study.Journal of pediatric gastroenterology and nutrition · 2025Article
- Functional maturation of preterm intestinal epithelium through CFTR activation.Communications biology · 2025Article
- Retrospective Analysis of Neonatal Surgery at Tottori University over the Past Ten Years.Yonago acta medica · 2023Article
- Clinical and growth outcomes after meconium-related ileus improved with Gastrografin enema in very low birth weight infants.PloS one · 2022Article
- Increased Risk of Meconium-Related Ileus in Extremely Premature Infants Exposed to Antenatal Magnesium Sulfate.Neonatology · 2022Article
- Loop Ileostomy in Europe's Tiniest Male Newborn for Meconium-Related Ileus.European journal of pediatric surgery reports · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Very low birth weight (VLBW) neonates experience various problems, including meconium-related ileus (MRI). This study investigated the risk factors of MRI and surgical MRI in VLBW infants. VLBW neonates admitted to the Neonatal Intensive Care Unit of Seoul National University Children's Hospital from October 2002 to September 2016 were included in the study. The diagnostic criteria for MRI were a decreased frequency of defecation with intolerable feeding, vomiting, and increased gastric residue (>50%); meconium-filled bowel dilatation in an imaging study; and no evidence of necrotizing enteritis or spontaneous intestinal perforation. Medical MRIs and surgical MRIs were managed through conventional treatment and surgical intervention. Of 1543 neonates, 69 and 1474 were in the patient and control groups, respectively. The risk factors for MRI include low birth weight (BW), cesarean section delivery, fetal distress, maternal diabetes, maternal hypertension, and maternal steroid use. Low BW and fetal distress were independent risk factors for MRI. Compared to the medical MRI group (n = 44), the risk factors for surgical MRI (n = 25) included males, younger gestational age, low BW, and meconium located at the small bowel. Male gender and low BW were independent risk factors for surgical MRI. Low BW and fetal distress were independent risk factors for MRI and male gender and low BW were independent risk factors for surgical MRI. In VLBW neonates, careful attention to the risk factors for MRI could minimize or avoid surgical interventions.
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