ArticleScientific reports2020
Fabrication of microfluidic device for Aflatoxin M1 detection in milk samples with specific aptamers.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 79 citations in OpenAlex.
- Microfluidic pretreatment devices for milk safety at the point of care.Mikrochimica acta · 2026Review
- MOF-based fluorescent molecularly imprinted polymer nanosensor for the determination of aflatoxin M1 in water and cow milk with exceptional sensitivity.RSC advances · 2026Article
- SELEX-Based Aptamer Technologies for Toxin Analysis: Screening, Optimization, and Computational Assisted Design.Toxins · 2026Review
- Review
- Emerging biosensors integrated with microfluidic devices: a promising analytical tool for on-site detection of mycotoxins.NPJ science of food · 2025Review
- Assembly of adaptive engineering aptamers for Escherichia coli and their application in all-in-one rapid detection.Mikrochimica acta · 2025Article
- pH and NaCl Optimisation to Improve the Stability of Gold and Silver Nanoparticles' Anti-Zearalenone Antibody Conjugates for Immunochromatographic Assay.Methods and protocols · 2023Article
- Emerging 0D, 1D, 2D, and 3D nanostructures for efficient point-of-care biosensing.Biosensors & bioelectronics: X · 2022Article
- Recent Advances in Electrochemical Biosensors for the Detection ofBiosensors · 2022Review
- Review
- Article
- Molecular Diagnostic of Ochratoxin A With Specific Aptamers in Corn and Groundnut via Fabrication of a Microfluidic Device.Frontiers in nutrition · 2022Article
- Lab-on-a-chip technologies for food safety, processing, and packaging applications: a review.Environmental chemistry letters · 2022Review
- Label-free detection of SARS-CoV-2 Spike S1 antigen triggered by electroactive gold nanoparticles on antibody coated fluorine-doped tin oxide (FTO) electrode.Analytica chimica acta · 2021Article
- Disposable Paper-Based Biosensors for the Point-of-Care Detection of Hazardous Contaminations-A Review.Biosensors · 2021Review
- Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk.Micromachines · 2021Review
- Review
- Using Aptamers as a Novel Method for Determining GnRH/LH Pulsatility.International journal of molecular sciences · 2020Review
- Electrochemical analysis of anionic analytes in weakly supported media using electron transfer promotion effect: a case study on nitrite.Scientific reports · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
This study describes the colorimetric detection of aflatoxin M1 (Afl M1) in milk samples using a microfluidic paper-based analytical device (µPAD). Fabrication of µPADs was done using a simple and quick approach. Each μPAD contained a detection zone and a sample zone interconnected by microchannels. The colorimetric assay was developed using unmodified AuNPs as a probe and 21-mer aptamer as a recognition molecule. The free aptamers were adsorbed onto the surface of AuNPs in absence of Afl M1, even at high salt concentrations. The salt induced aggregation of specific aptamers occurred in presence of Afl M1. Under optimum conditions, the analytical linear range was found to be 1 µM to 1 pM with limit of detection 3 pM and 10 nM in standard buffer and spiked milk samples respectively. The proposed aptamer based colorimetric assay was repeatable, quick, selective, and can be used for on-site detection of other toxins in milk and meat samples.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.