ArticleNature communications2020
Cell lineage-specific transcriptome analysis for interpreting cell fate specification of proembryos.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed.
- Maternal epigenetic regulation of embryonic patterning in plants.Nature plants · 2026Article
- Molecular understanding of plant pollination, fertilization, seed development and protoplast regeneration.Science China. Life sciences · 2026Review
- PLETHORA transcription factors promote early embryo development through induction of meristematic potential.Development (Cambridge, England) · 2024Article
- Autophagy-mediated degradation of integumentary tapetum is critical for embryo pattern formation.Nature communications · 2024Article
- Whole-mount RNA in situ hybridization technique in Torenia ovules.Plant reproduction · 2023Article
- Cancer-associated fibroblast-specific lncRNA LINC01614 enhances glutamine uptake in lung adenocarcinoma.Journal of hematology & oncology · 2022Article
- Review
- Gene expression variation in Arabidopsis embryos at single-nucleus resolution.Development (Cambridge, England) · 2021Article
- Small Non-Coding RNAs at the Crossroads of Regulatory Pathways Controlling Somatic Embryogenesis in Seed Plants.Plants (Basel, Switzerland) · 2021Review
- Developmental and genomic architecture of plant embryogenesis: from model plant to crops.Plant communications · 2021Review
- TheQuantitative plant biology · 2021Review
- Zygotic Embryogenesis in Flowering Plants.Methods in molecular biology (Clifton, N.J.) · 2021Review
- Genetic activity during early plant embryogenesis.The Biochemical journal · 2020Review
- Intracellular dynamics and transcriptional regulations in plant zygotes: a case study of Arabidopsis.Plant reproduction · 2020Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Arabidopsis, a zygote undergoes asymmetrical cell division that establishes the first two distinct cell types of early proembryos, apical and basal cells. However, the genome-wide transcriptional activities that guide divergence of apical and basal cell development remain unknown. Here, we present a comprehensive transcriptome analysis of apical and basal cell lineages, uncovering distinct molecular pathways during cell lineage specification. Selective deletion of inherited transcripts and specific de novo transcription contribute to the establishment of cell lineage-specific pathways for cell fate specification. Embryo-related pathways have been specifically activated in apical cell lineage since 1-cell embryo stage, but quick transcriptome remodeling toward suspensor-specific pathways are found in basal cell lineage. Furthermore, long noncoding RNAs and alternative splicing isoforms may be involved in cell lineage specification. This work also provides a valuable lineage-specific transcriptome resource to elucidate the molecular pathways for divergence of apical and basal cell lineages at genome-wide scale.
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Registered trials
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