ArticleNature communications2020
An ankyrin-repeat and WRKY-domain-containing immune receptor confers stripe rust resistance in wheat.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 1 of them a synthesis that pooled it.
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Who cites it
90 citing papers in PubMed, 1 synthesis or guideline pooled it, 175 citations in OpenAlex.
- Meta-QTLs and candidate genes for stripe rust resistance in wheat.Scientific reports · 2021Pooled it
- Transcriptional and Functional Insights Into the All-Stage Resistance Gene GmRmd1-Mediated Regulation of Resistance to Powdery Mildew in Soybean.Molecular plant pathology · 2026Article
- A transmembrane protein confers the Yr26/Yr24/YrCH42/YrG22-mediated stripe rust resistance in wheat.Nature communications · 2026Article
- From QTL to candidate genes: a data-driven approach to unravel the genetic architecture of yellow rust resistance in central European wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Development of Hexaploid Wheat Germplasm with Resistance to Both Powdery Mildew and Stripe Rust by Introgression ofPlants (Basel, Switzerland) · 2026Article
- High‑density mapping of stripe rust resistance gene YrH8 in wheat line Hangmai 8.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Genetic analysis and mapping of adult plant stripe rust resistance loci in CIMMYT wheat 'Kijil' under Mexican and Chinese field environments.PLoS genetics · 2026Article
- Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance.The plant genome · 2026Review
- The annotated blueprint: integrated functional genomic resources for a model tetraploid wheat Triticum turgidum cv Kronos.The New phytologist · 2026Article
- LOX-A4 shapes Triticum urartu gene pools and contributions to the A subgenome of polyploid wheat.Nature communications · 2026Article
- Escalating Threat of Wheat Stripe Rust Under Climate Change: Pathogen Evolution, Resistance Durability, and Future Management.Plants (Basel, Switzerland) · 2026Review
- Identification of stripe rust adult plant resistance genes in the hard winter wheat cultivar Baker's Ann.The plant genome · 2026Article
- Genome-wide identification of the GATA transcription factor family in ten Cucurbitaceae species and expression analysis of ClGATA genes in watermelon stress responses.BMC genomics · 2026Article
- Unveiling the genetic architecture of stripe rust resistance in wheat: a region-specific GWAS in Xinjiang, China.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Unlocking the genetic potential ofFrontiers in plant science · 2026Review
- The Landscape of Integrated Domains of Angiosperm NLR Genes Reveals Continuous Architecture Evolution of Plant Intracellular Immune Receptors.Plants (Basel, Switzerland) · 2025Article
- Mapping novel yellow and leaf rust loci and predicting resistance in cross derived Canadian durum wheat.The plant genome · 2025Article
- Loss of calcium-dependent protein kinases OsCPK5 and OsCPK13 leads to NLR-dependent resistance in rice.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The Annotated Blueprint: Integrated Functional Genomic Resources for a model Tetraploid WheatbioRxiv : the preprint server for biology · 2025Article
- Identification of Leaf Rust-Related Gene Signature in Wheat (Triticum Aestivum L.) Using High-Throughput Sequencing, Network Analysis, and Machine Learning Algorithms.Rice (New York, N.Y.) · 2025Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Perception of pathogenic effectors in plants often relies on nucleotide-binding domain (NBS) and leucine-rich-repeat-containing (NLR) proteins. Some NLRs contain additional domains that function as integrated decoys for pathogen effector targets and activation of immune signalling. Wheat stripe rust is one of the most devastating diseases of crop plants. Here, we report the cloning of YrU1, a stripe rust resistance gene from the diploid wheat Triticum urartu, the progenitor of the A genome of hexaploid wheat. YrU1 encodes a coiled-coil-NBS-leucine-rich repeat protein with N-terminal ankyrin-repeat and C-terminal WRKY domains, representing a unique NLR structure in plants. Database searches identify similar architecture only in wheat relatives. Transient expression of YrU1 in Nicotiana benthamiana does not induce cell death in the absence of pathogens. The ankyrin-repeat and coiled-coil domains of YrU1 self-associate, suggesting that homodimerisation is critical for YrU1 function. The identification and cloning of this disease resistance gene sheds light on NLR protein function and may facilitate breeding to control the devastating wheat stripe rust disease.
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