Evidence map›Paper›PMID 32170046›Full record

ArticleAging2020

Development and validation of a nomogram for preoperative prediction of cervical lymph node involvement in thyroid microcarcinoma.

Si Lu, Rongjie Zhao, Yeqin Ni, Jinwang Ding, Fuqiang Qiu, You Peng, Gang Pan, Fan Wu, Yu Zhang, Jingjing Shi and 2 more

Abstract readValidation Study
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  3. A CT based radiomics analysis to predict the CN0 status of thyroid papillary carcinoma: a two- center study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Si LuZhejiang Chinese Medical University Affiliated Hangzhou First Hospital, Hangzhou First People's Hospital, Hangzhou 310006, Zhejiang, China.
Rongjie ZhaoDepartment of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang, China.
Yeqin NiZhejiang Chinese Medical University Affiliated Hangzhou First Hospital, Hangzhou First People's Hospital, Hangzhou 310006, Zhejiang, China.
Jinwang DingDepartment of Oncological Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang, China.
Fuqiang QiuDepartment of Ultrasound, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, Zhejiang, China.
You PengDepartment of Oncological Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang, China.
Gang PanDepartment of Oncological Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang, China.
Fan WuZhejiang Chinese Medical University Affiliated Hangzhou First Hospital, Hangzhou First People's Hospital, Hangzhou 310006, Zhejiang, China.
Yu ZhangDepartment of Oncological Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang, China.
Jingjing ShiDepartment of Oncological Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang, China.
Tianhan ZhouZhejiang Chinese Medical University Affiliated Hangzhou First Hospital, Hangzhou First People's Hospital, Hangzhou 310006, Zhejiang, China.
Dingcun LuoDepartment of Oncological Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical regional lymph node involvement (CRLNI) is common in papillary thyroid microcarcinoma (PTMC), but the way to deal with cervical lymph node involvement of clinically negative PTMC is controversial. We studied data of patients histologically confirmed PTMC in the Surveillance, Epidemiology, and End Results (SEER) Program and Department of Surgical Oncology in Hangzhou First People's Hospital (China). We screened 6 variables of demographic and clinicopathological characteristics as potential predictors and further constructed a lymph node involvement model based on the independent predictors including age, race, sex, extension, multifocality and tumor size. The model was validated by both the internal and the external testing sets, and the visual expression of the model was displayed by a nomogram. As a result, the C-index of this predictive model in the training set was 0.766, and the internal and external testing sets through cross-validation were 0.753 and 0.668, respectively. The area under the receiver operating characteristic curve (AUC) was 0.766 for the training set. We also performed a Decision Curve Analysis (DCA), which showed that predicting the cervical lymph node involvement risk applying this nomogram would be better than having all patients or none patients use this nomogram.

Indexed as

NomogramsCarcinoma, PapillaryFemaleHumansLymph NodesMaleMiddle AgedNeckPreoperative CareSensitivity and SpecificityThyroid Neoplasmscervical regional lymph node involvementmodelnomogrampapillary thyroid microcarcinomaSEER

Identifiers

PMID32170046
PMCPMC7138557

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.