ArticleProceedings of the National Academy of Sciences of the United States of America2020
A pair of esterases from a commensal gut bacterium remove acetylations from all positions on complex β-mannans.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 42 citations in OpenAlex.
- Metabolism of β-mannans by representative, understudied Bacillota species from the human colon.FEMS microbiology ecology · 2026Article
- Deacetylation of β-Mannans by Two Complementary Carbohydrate Esterases from the Human Gut MicrobeBiochemistry · 2026Article
- Studies on the concerted interaction of microbes in the gastrointestinal tract of ruminants on lignocellulose and its degradation mechanism.Frontiers in microbiology · 2025Review
- Current models in bacterial hemicellulase-encoding gene regulation.Applied microbiology and biotechnology · 2024Review
- The need for high-resolution gut microbiome characterization to design efficient strategies for sustainable aquaculture production.Communications biology · 2024Article
- Towards an understanding of the enzymatic degradation of complex plant mannan structures.World journal of microbiology & biotechnology · 2023Review
- Carbohydrate esterases involved in deacetylation of food components by the human gut microbiota.Essays in biochemistry · 2023Article
- The SGNH hydrolase family: a template for carbohydrate diversity.Glycobiology · 2022Review
- Synthesis and mammalian cell compatibility of light-released glycan precursors for controlled metabolic engineering.Bioorganic & medicinal chemistry · 2022Article
- An Immunological Polysaccharide fromInternational journal of molecular sciences · 2022Article
- Xyloglucan processing machinery in Xanthomonas pathogens and its role in the transcriptional activation of virulence factors.Nature communications · 2021Article
- Article
- CE16 acetylesterases: in silico analysis, catalytic machinery prediction and comparison with related SGNH hydrolases.3 Biotech · 2021Article
- Review
- Ascertaining the biochemical function of an essential pectin methylesterase in the gut microbeThe Journal of biological chemistry · 2020Article
- Microbiota-directed fibre activates both targeted and secondary metabolic shifts in the distal gut.Nature communications · 2020Article
- Origin and Evolution ofMicroorganisms · 2020Article
- Molecular Mechanism of Polysaccharide Acetylation by the Arabidopsis XylanThe Plant cell · 2020Article
- Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
β-mannans and xylans are important components of the plant cell wall and they are acetylated to be protected from degradation by glycoside hydrolases. β-mannans are widely present in human and animal diets as fiber from leguminous plants and as thickeners and stabilizers in processed foods. There are many fully characterized acetylxylan esterases (AcXEs); however, the enzymes deacetylating mannans are less understood. Here we present two carbohydrate esterases,
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