Evidence map›Paper›PMID 32169921›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

Initial Clinical Results of a Novel Immuno-PET Theranostic Probe in Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer.

Caroline Rousseau, David M Goldenberg, Mathilde Colombié, Jean-Charles Sébille, Philippe Meingan, Ludovic Ferrer, Pierre Baumgartner, Evelyne Cerato, Damien Masson, Mario Campone and 10 more

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Prospective pilot study with [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  2. Review
  3. Monitoring Pharmacological Treatment of Breast Cancer with MRI.Current issues in molecular biology · 2025
    Review
  4. Ultra-low dose immunoPET usingFrontiers in medicine · 2025
    Article
  5. Review
  6. Nuclear Imaging of Bispecific Antibodies on the Rise.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Review
  7. Engineered Antibodies as Cancer Radiotheranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  8. Review
  9. In Regard to Trotter et al.Advances in radiation oncology · 2024
    Article
  10. Review
  11. Review
  12. Review
  13. Antibody Engineering for Nuclear Imaging and Radioimmunotherapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  14. Pretargeting: A Path Forward for Radioimmunotherapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Current Landscape in Clinical Pretargeted Radioimmunoimaging and Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Caroline RousseauNuclear Medicine, ICO Cancer Center, Nantes, France c-rousseau@ico.unicancer.fr.
David M GoldenbergImmunomedics, Inc., Morris Plains, New Jersey.
Mathilde ColombiéNuclear Medicine, ICO Cancer Center, Nantes, France.
Jean-Charles SébilleNuclear Medicine, ICO Cancer Center, Nantes, France.
Philippe MeinganRadiology, ICO Cancer Center, Nantes, France.
Ludovic FerrerCRCINA, University of Nantes, INSERM UMR1232, CNRS-ERL6001, Nantes, France.
Pierre BaumgartnerPharmacy, ICO Cancer Center, Nantes, France.
Evelyne CeratoDRCI, University Hospital, Nantes, France.
Damien MassonBiology Department, University Hospital, Nantes, France.
Mario CamponeOncology, ICO Cancer Center, Nantes, France.
Aurore RauscherPharmacy, ICO Cancer Center, Nantes, France.
Vincent FleuryNuclear Medicine, ICO Cancer Center, Nantes, France.
Catherine LabbeRadiology, ICO Cancer Center, Nantes, France.
Alain Faivre ChauvetNuclear Medicine, University Hospital, Nantes, France.
Jean-Sebastien FresnelOncology, ICO Cancer Center, Nantes, France.
Claire ToquetPathology Department, University Hospital, Nantes, France.
Jacques BarbetGIP Arronax, Saint-Herblain, France; and.
Robert M SharkeyImmunomedics, Inc., Morris Plains, New Jersey.
Loic CampionCRCINA, University of Nantes, INSERM UMR1232, CNRS-ERL6001, Nantes, France.
Françoise Kraeber-BodéréNuclear Medicine, ICO Cancer Center, Nantes, France.
Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers · FRNantes Université · FRInstitut Génétique Nantes Atlantique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This prospective study evaluated the imaging performance of a novel pretargeting immunologic PET (immuno-PET) method in patients with human epidermal growth factor receptor 2 (HER2)-negative, carcinoembryonic antigen (CEA)-positive metastatic breast cancer, compared with CT, bone MRI, and

Indexed as

Fluorodeoxyglucose F18Positron-Emission TomographyAdultBreast NeoplasmsErb-b2 Receptor Tyrosine KinasesFemaleHumansMiddle AgedPrecision MedicineProspective StudiesERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesFluorodeoxyglucose F1868Gabispecific antibodybreast cancerimmuno-PETpretargeting

Identifiers

PMID32169921
PMCPMC7413237
OpenAlexW3012196714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.