Evidence map›Paper›PMID 32169919›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

Biokinetics of Radiolabeled Monoclonal Antibody BC8: Differences in Biodistribution and Dosimetry Among Hematologic Malignancies.

Manuela Matesan, Darrell R Fisher, Roger Wong, Ajay K Gopal, Damian J Green, Brenda M Sandmaier, William Bensinger, John M Pagel, Johnnie Orozco, Oliver W Press and 6 more

Open access · bronzeAbstract readClinical Trial, Phase IClinical Trial, Phase IIComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Manuela MatesanDepartment of Radiology, University of Washington, Seattle, Washington mmatesan@u.washington.edu.
Darrell R FisherDepartment of Radiology, University of Washington, Seattle, Washington.
Roger WongDepartment of Radiology, University of Washington, Seattle, Washington.
Ajay K GopalFred Hutchinson Cancer Research Center, Seattle, Washington.
Damian J GreenFred Hutchinson Cancer Research Center, Seattle, Washington.
Brenda M SandmaierFred Hutchinson Cancer Research Center, Seattle, Washington.
William BensingerSwedish Cancer Institute, Seattle, Washington.
John M PagelSwedish Cancer Institute, Seattle, Washington.
Johnnie OrozcoFred Hutchinson Cancer Research Center, Seattle, Washington.
Oliver W PressFred Hutchinson Cancer Research Center, Seattle, Washington.
Ryan D CassadayFred Hutchinson Cancer Research Center, Seattle, Washington.
Eric HutchinsonDepartment of Radiology, University of Washington, Seattle, Washington.
Michelle WannerDepartment of Radiology, University of Washington, Seattle, Washington.
Sujit PalDepartment of Radiology, University of Washington, Seattle, Washington.
Carolyn ThostensonDepartment of Radiology, University of Washington, Seattle, Washington.
Joseph G RajendranDepartment of Radiology, University of Washington, Seattle, Washington.
University of Washington · USFred Hutch Cancer Center · USSwedish Medical Center · US

Funding

Radioimmunotherapy Combinations for B-cell MalignancyR01CA076287 · NCI · UNIVERSITY OF WASHINGTON · PI GREEN, DAMIAN J. · 1998 to 2025
$8.1M
Targeted Alpha Radioimmunotherapy with Haploidentical Bone Marrow Transplantation for AMLK01CA188151 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI OROZCO, JOHNNIE JOSE · 2015 to 2019
$845k
Targeted Radiotherapy with 90Y-BC8 Monclonal Antibody, Fludarabine and TBI FollowR21CA155911 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GREEN, DAMIAN J. · 2011 to 2012
$693k
NCI NIH HHS K01 CA188151NCI NIH HHS R01 CA076287NCI NIH HHS R21 CA155911
6 · The paper itself

Abstract

We reviewed

Indexed as

AdultAgedAntibodies, MonoclonalFemaleHematologic NeoplasmsHeterocyclic Compounds, 1-RingHumansIndium RadioisotopesIsotope LabelingKineticsLeukocyte Common AntigensMaleMiddle AgedRadiometryTissue Distribution1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidAntibodies, MonoclonalHeterocyclic Compounds, 1-RingIndium-111Indium RadioisotopesLeukocyte Common Antigensanti-CD45BC8dosimetryradioimmunotherapy

Identifiers

PMID32169919
PMCPMC7456175
OpenAlexW3010987969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.