Evidence map›Paper›PMID 32169905›Full record

ArticleThe Journal of biological chemistry2020

The transcriptional regulator MEIS2 sets up the ground state for palatal osteogenesis in mice.

Linyan Wang, Qinghuang Tang, Jue Xu, Hua Li, Tianfang Yang, Liwen Li, Ondrej Machon, Tao Hu, YiPing Chen

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

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  10. Single cell sequencing of the mouse anterior palate reveals mesenchymal heterogeneity.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
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  14. Meis2 controls skeletal formation in the hyoid region.Frontiers in cell and developmental biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Linyan WangState Key Laboratory of Oral Diseases, Department of Preventive Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China; Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana 70118.
Qinghuang TangDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana 70118.
Jue XuDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana 70118; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, Sichuan, China.
Hua LiDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana 70118.
Tianfang YangDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana 70118.
Liwen LiDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana 70118.
Ondrej MachonDepartment of Developmental Biology, Institute of Experimental Medicine of the Czech Academy of Sciences, 14200 Praha, Czech Republic.
Tao HuState Key Laboratory of Oral Diseases, Department of Preventive Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China.
YiPing ChenDepartment of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana 70118. Electronic address: ychen@tulane.edu.
Tulane University · USCzech Academy of Sciences, Institute of Experimental Medicine · CZSichuan University · CN

Funding

Molecular patterning of the hard palate during palatogenesisR01DE026482 · NIDCR · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, YIPING · 2017 to 2021
$1.8M
NIDCR NIH HHS R01 DE026482
6 · The paper itself

Abstract

Haploinsufficiency of Meis homeobox 2 (

Indexed as

OsteogenesisAnimalsBinding SitesGene Expression Regulation, DevelopmentalHomeodomain ProteinsMiceMice, Inbred C57BLNeural CrestNeural Stem CellsPalateProtein BindingHomeodomain ProteinsMrg1 protein, mouseShox2 protein, mousebonechromatin accessibilitycraniofacial developmentgene knockoutgene regulationMeis homeobox 2 (MEIS2)osteogenesispalatal developmentshort stature homeobox 2 (SHOX2)transcriptiontranscription factortransgenic mice

Identifiers

PMID32169905
PMCPMC7170518
OpenAlexW3011884295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.