ArticleThe international journal of behavioral nutrition and physical activity2020
Accelerometer-measured physical activity and sedentary time in a cohort of US adults followed for up to 13 years: the influence of removing early follow-up on associations with mortality.
Article in The international journal of behavioral nutrition and physical activity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies.British journal of sports medicine · 2022Pooled it
- Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts.The Lancet. Public health · 2022Pooled it
- Joint associations of accelero-meter measured physical activity and sedentary time with all-cause mortality: a harmonised meta-analysis in more than 44 000 middle-aged and older individuals.British journal of sports medicine · 2020Pooled it
- Impact of physical activity patterns on major adverse cardiovascular events in adults with hypertension.British journal of sports medicine · 2026Article
- Vigorous intermittent lifestyle physical activity (VILPA) and mortality risk among US adults: a wearables-based national cohort study.The international journal of behavioral nutrition and physical activity · 2026Article
- High BMI and low cardiorespiratory fitness in adolescence are associated with increased risk of severe bacterial infections in adulthood.Journal of internal medicine · 2026Article
- Associations of accelerometer-measured light-intensity physical activity with mortality and incidence of cardiovascular diseases and cancers: A prospective cohort study.Journal of sport and health science · 2025Article
- Wearable device-based health equivalence of different physical activity intensities against mortality, cardiometabolic disease, and cancer.Nature communications · 2025Article
- Associations of objectively measured physical activity and sedentary time with all-cause mortality in Japanese older adults: a 10-year prospective study.British journal of sports medicine · 2025Article
- The association of physical activity fragmentation with all-cause mortality in Hispanics: a prospective cohort study.Lancet regional health. Americas · 2025Article
- Data Analytics in Physical Activity Studies With Accelerometers: Scoping Review.Journal of medical Internet research · 2024Article
- Do the associations of daily steps with mortality and incident cardiovascular disease differ by sedentary time levels? A device-based cohort study.British journal of sports medicine · 2024Article
- Joint associations of device-measured physical activity and abdominal obesity with incident cardiovascular disease: a prospective cohort study.British journal of sports medicine · 2024Article
- Dose-response associations, physical activity intensity and mortality risk: A narrative review.Journal of sport and health science · 2024Review
- Prospective Associations of Different Combinations of Aerobic and Muscle-Strengthening Activity With All-Cause, Cardiovascular, and Cancer Mortality.JAMA internal medicine · 2023Article
- Review
- Profile of leisure-time physical activity and sedentary behavior in adults in Brazil: a nationwide survey, 2019.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2023Article
- Vigorous physical activity, incident heart disease, and cancer: how little is enough?European heart journal · 2022Article
- GRANADA consensus on analytical approaches to assess associations with accelerometer-determined physical behaviours (physical activity, sedentary behaviour and sleep) in epidemiological studies.British journal of sports medicine · 2022Article
- Associations of Daily Steps and Step Intensity With Incident Diabetes in a Prospective Cohort Study of Older Women: The OPACH Study.Diabetes care · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObservational studies linking physical activity with mortality are susceptible to reverse causation bias from undiagnosed and prevalent diseases. Researchers often attempt to deal with reverse causation bias by excluding deaths occurring within the first 1 or 2 years from the analysis, but it is unclear if excluding deaths within this time-frame is sufficient to remove bias.
methodsWe examined associations between total and intensity-specific physical activity and sedentary time with all-cause mortality in a prospective cohort of 3542 individuals from the 2003-2006 NHANES cycles. In order to yield measures of association hypothesized as minimally influenced by reverse causation bias the primary analysis excluded individuals with < 5 years of follow-up. Accelerometer-measured physical activity was linked with recently updated vital status from the National Death Index with a median follow-up of 10.8 years.
resultsHazard ratios (95% confidence intervals) were 0.74 (0.53, 1.04), 0.52 (0.37, 0.73), and 0.61 (0.38, 1.01) for ascending quartiles of total physical activity against the least active reference. Hazard ratios for ascending moderate-to-vigorous physical activity quartiles against the reference were 0.67 (0.47, 1.96), 0.67 (0.47, 0.95), and 0.68 (0.39, 1.18). Associations for light intensity physical activity and sedentary time were smaller in magnitude and all confidence intervals included unity. Total activity and moderate-to-vigorous physical activity hazard ratios from analyses only excluding deaths within the first 2 years were inflated by 13 and 26% relative to analysis restricted to ≥5 years of follow-up.
conclusionsThe pattern of associations suggested total physical activity and moderate-to-vigorous physical activity were associated with lower mortality after more than 10 years of follow-up and excluding the first 5 years of observation time to minimize the impact of reverse causation bias. Excluding deaths within the first 2 years appeared insufficient to minimize the impact of reserve causation bias.
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