Evidence map›Paper›PMID 32168951›Full record

ArticleInternational journal of molecular sciences2020

NEAT1 is Required for the Expression of the Liver Cancer Stem Cell Marker CD44.

Shigemi Koyama, Hiroyuki Tsuchiya, Masataka Amisaki, Hiromi Sakaguchi, Soichiro Honjo, Yoshiyuki Fujiwara, Goshi Shiota

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

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  11. Subpopulation cooperation renders drug resistance of hepatobiliary tumor organoids.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2022
    Article
  12. Article
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  14. International journal of molecular sciences · 2022
    Article
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  18. Article
  19. Immune evasion by cancer stem cells.Regenerative therapy · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shigemi KoyamaDivision of Molecular and Genetic Medicine, Graduate School of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan.
Hiroyuki TsuchiyaDivision of Molecular and Genetic Medicine, Graduate School of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan.ORCID 0000-0002-2144-8272
Masataka AmisakiDivision of Surgical Oncology, Department of Surgery, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan.
Hiromi SakaguchiDivision of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan.
Soichiro HonjoDivision of Surgical Oncology, Department of Surgery, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan.ORCID 0000-0001-9319-1974
Yoshiyuki FujiwaraDivision of Surgical Oncology, Department of Surgery, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan.
Goshi ShiotaDivision of Molecular and Genetic Medicine, Graduate School of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan.
Tottori University · JP

Funding

Japan Society for the Promotion of Science JP16K09359Japan Society for the Promotion of Science JP19K08469
6 · The paper itself

Abstract

CD44, a cancer stem cell (CSC) marker, is required for maintaining CSC properties in hepatocellular carcinoma (HCC). Nuclear enriched abundant transcript 1 (NEAT1), a long noncoding RNA (lncRNA), is an oncogenic driver in HCC. In the present study, we investigated the significance of the

Indexed as

Biomarkers, TumorCarcinoma, HepatocellularCell Line, TumorGene Expression Regulation, NeoplasticHep G2 CellsHumansHyaluronan ReceptorsLiver NeoplasmsNeoplastic Stem CellsPrognosisRNA, Long NoncodingSpheroids, CellularUp-RegulationBiomarkers, TumorCD44 protein, humanHyaluronan ReceptorsNEAT1 long non-coding RNA, humanRNA, Long Noncodingcancer stem cellsCD44hepatocellular carcinomaNEAT1spheroid

Identifiers

PMID32168951
PMCPMC7139689
OpenAlexW3012001878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.