Evidence map›Paper›PMID 32168919›Full record

ArticleInternational journal of molecular sciences2020

Fibroblast Interaction with Different Abutment Surfaces: In Vitro Study.

Luigi Canullo, Tullio Genova, Esperanza Gross Trujillo, Guillermo Pradies, Sara Petrillo, Maurizio Muzzi, Stefano Carossa, Federico Mussano

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Crystallinity of TiOJournal of materials science. Materials in medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luigi CanulloPrivate Practice, Via Nizza, 46, 00198 Rome, Italy.ORCID 0000-0001-9875-2929
Tullio GenovaDepartment of Life Sciences and Systems Biology, University of Torino, 10126 Turin, Italy.ORCID 0000-0001-7824-8389
Esperanza Gross TrujilloDepartment of Buccofacial Prosthesis, University Complutense, 28040 Madrid, Spain.
Guillermo PradiesDepartment of Buccofacial Prosthesis, University Complutense, 28040 Madrid, Spain.
Sara PetrilloDepartment of Molecular Biotechnology and Health Sciences, University of Rome III, 00133 Rome, Italy.
Maurizio MuzziDepartment of Science, University of Rome III, 00133 Rome, Italy.
Stefano CarossaCIR Dental School-Department of Surgical Sciences, University of Torino, Via Nizza 230, 10126 Turin, Italy.
Federico MussanoCIR Dental School-Department of Surgical Sciences, University of Torino, Via Nizza 230, 10126 Turin, Italy.ORCID 0000-0001-5800-0749

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca Dipartimenti di Eccellenza ex L.232/2016
6 · The paper itself

Abstract

backgroundAttaining an effective mucosal attachment to the transmucosal part of the implant could protect the peri-implant bone.

aimTo evaluate if chair side surface treatments (plasma of Argon and ultraviolet light) may affect fibroblast adhesion on different titanium surfaces designed for soft tissue healing.

methodsGrade 5 titanium discs with four different surface topographies were subdivided into 3 groups: argon-plasma; ultraviolet light, and no treatment. Cell morphology and adhesion tests were performed at 20 min, 24 h, and 72 h.

resultsQualitative observation of the surfaces performed at the SEM was in accordance with the anticipated features. Roughness values ranged from smooth (MAC Sa = 0.2) to very rough (XA Sa = 21). At 20 min, all the untreated surfaces presented hemispherical cells with reduced filopodia, while the cells on treated samples were more spread with broad lamellipodia. However, these differences in spreading behavior disappeared at 24 h and 72 h. Argon-plasma, but not UV, significantly increased the number of fibroblasts independently of the surface type but only at 20 min. Statistically, there was no surface in combination with a treatment that favored a greater cellular adhesion.

conclusionsData showed potential biological benefits of treating implant abutment surfaces with the plasma of argon in relation to early-stage cell adhesion.

Indexed as

ArgonCell AdhesionCell ProliferationCells, CulturedFibroblastsHumansIn Vitro TechniquesSurface PropertiesTitaniumArgonTitaniumabutment characteristicsabutment integrationbioactivationdental implant abutmentfibroblastin vitro studyplasma of argonUV light

Identifiers

PMID32168919
PMCPMC7139398

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.