Dissolution Behavior of Flufenamic Acid in Heated Mixtures with Nanocellulose.

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.3field-weighted citation impact, top 50% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

Expression and functions of N-type Cav2.2 and T-type Cav3.1 channels in rat vasopressin neurons under normotonic conditions.The journal of physiological sciences : JPS · 2020
Article
Transition Metal Complexes with Flufenamic Acid for Pharmaceutical Applications-A Novel Three-Centered Coordination Polymer of Mn(II) Flufenamate.Materials (Basel, Switzerland) · 2020
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Athanasios MantasNanotechnology and Functional Materials, Department of Materials Science and Engineering, Box 534 Uppsala University, 75121 Uppsala, Sweden.ORCID 0000-0001-5547-7816

Albert MihranyanNanotechnology and Functional Materials, Department of Materials Science and Engineering, Box 534 Uppsala University, 75121 Uppsala, Sweden.ORCID 0000-0002-8105-2317

Uppsala University · SE

Funding

Knut och Alice Wallenbergs Stiftelse Bridge grant 2018.01141

6 · The paper itself

Abstract

Flufenamic acid (FFA) is a problem drug that has up to eight different polymorphs and shows poor solubility. Variability in bioavailability has been reported in the past resulting in limited use of FFA in the oral solid dosage form. The goal of this article was to investigate the polymorphism and amorphization behavior of FFA in non-heated and heated mixtures with high surface area nanocellulose, i.e.,

Indexed as

Anti-Inflammatory AgentsBiomimetic MaterialsCelluloseChemistry, PharmaceuticalDrug StabilityFlufenamic AcidGastric JuiceHot TemperatureHumansNanostructuresSolubilityAnti-Inflammatory AgentsCelluloseFlufenamic Acidmicrocrystalline celluloseCladophora cellulosefasted/fed state variabilityfenamatesmicrocrystalline cellulosepolymorphism

Identifiers

PMID32168901

DOI10.3390/molecules25061277

PMCPMC7144018

OpenAlexW3011970117

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.