Evidence map›Paper›PMID 32168864›Full record

ReviewJournal of fungi (Basel, Switzerland)2020

Applying the Host-Microbe Damage Response Framework to

Paul L Fidel, Junko Yano, Shannon K Esher, Mairi C Noverr

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. In vitro activities ofCurrent medical mycology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paul L FidelCenter of Excellence in Oral and Craniofacial Biology, Louisiana State University Health Sciences Center School of Dentistry, New Orleans, LA 70119, USA.
Junko YanoCenter of Excellence in Oral and Craniofacial Biology, Louisiana State University Health Sciences Center School of Dentistry, New Orleans, LA 70119, USA.
Shannon K EsherDepartment of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.ORCID 0000-0001-5212-0432
Mairi C NoverrDepartment of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Leigh Lamonica · 2012 to 2026
$69.1M
Candida mediated protection against polymicrobial sepsisR01AI145096 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI FIDEL, PAUL L, STEELE, CHAD · 2019 to 2023
$2.9M
Host and microbial factors promoting synergistic mortality during polymicrobial intra-abdominal infections with Candida albicans and Staphylococcus aureusR01AI116025 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI NOVERR, MAIRI C · 2015 to 2019
$1.8M
National Institute of Allergy and Infectious Diseases R01AI116025NIAID NIH HHS R01 AI145096NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Disease is a complex outcome that can occur as a result of pathogen-mediated damage, host-mediated damage or both. This has led to the revolutionary concept of the damage response framework (DRF) that defines microbial virulence as a function of host immunity. The DRF outlines six scenarios (classes) of host damage or beneficial outcomes, depending on the microbe and the strength of the immune response.

Indexed as

Candida albicansdamage responsehostimmune responsepathogenesis

Identifiers

PMID32168864
PMCPMC7151217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.