Evidence map›Paper›PMID 32168782›Full record

ArticleInternational journal of molecular sciences2020

NR2F2 Orphan Nuclear Receptor is Involved in Estrogen Receptor Alpha-Mediated Transcriptional Regulation in Luminal A Breast Cancer Cells.

Edina Erdős, Bálint László Bálint

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Multidimensional roles and clinical significance of GATA3 in breast cancer.Frontiers in cell and developmental biology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Edina ErdősGenomic Medicine and Bioinformatic Core Facility, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, 98 Nagyerdei krt., H-4032 Debrecen, Hungary.
Bálint László BálintGenomic Medicine and Bioinformatic Core Facility, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, 98 Nagyerdei krt., H-4032 Debrecen, Hungary.
University of Debrecen · HU

Funding

Debrecen Venture Catapult Program EFOP-3.6.1-16-2016-00022Hungarian Scientific Research Fund OTKA K 129166MOLMEDEX FUN-OMICS GINOP-2.3.3-15-2016-00007
6 · The paper itself

Abstract

Nuclear Receptor Subfamily 2 Group F Member 2 (NR2F2) is a member of the steroid/thyroid hormone receptor superfamily with a crucial role in organogenesis, angiogenesis, cardiovascular development and tumorigenesis. However, there is limited knowledge about the cistrome and transcriptome of NR2F2 in breast cancer. In this study, we mapped the regulatory mechanism by NR2F2 using functional genomic methods. To investigate the clinical significance of NR2F2 in breast cancer, The Cancer Genome Atlas (TCGA) data were used. These results show that a high

Indexed as

Breast NeoplasmsCell Line, TumorChromatin ImmunoprecipitationCOUP Transcription Factor IIEstrogen Receptor alphaFemaleGATA3 Transcription FactorGene Expression RegulationGene Expression Regulation, NeoplasticHepatocyte Nuclear Factor 3-alphaHigh-Throughput Nucleotide SequencingHumansMCF-7 CellsSequence Analysis, DNASurvival AnalysisUp-RegulationCOUP Transcription Factor IIESR1 protein, humanEstrogen Receptor alphaFOXA1 protein, humanGATA3 protein, humanGATA3 Transcription FactorHepatocyte Nuclear Factor 3-alphaNR2F2 protein, humanestrogen receptor alpha, NR2F2, cistrome, active histone modifications, chromatin interactions, breast cancer, luminal A subtype

Identifiers

PMID32168782
PMCPMC7139668
OpenAlexW3011390508

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.