Evidence map›Paper›PMID 32168764›Full record

ArticleGenes2020

CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen.

Yuxin Xu, Hongmei Liu, Huilin Pan, Xinyue Wang, Yuxin Zhang, Bing Yao, Nannan Li, Liangxue Lai, Zhanjun Li

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. V3: an enigmatic isoform of the proteoglycan versican.American journal of physiology. Cell physiology · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Five SNPs Within theFrontiers in genetics · 2021
    Article
  11. Review
  12. FGF5.Differentiation; research in biological diversity
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yuxin XuJilin Provincial Key Laboratory of Animal Embryo Engineering, Jilin University, Changchun 130062, China.
Hongmei LiuJilin Provincial Key Laboratory of Animal Embryo Engineering, Jilin University, Changchun 130062, China.
Huilin PanJilin Provincial Key Laboratory of Animal Embryo Engineering, Jilin University, Changchun 130062, China.
Xinyue WangJilin Provincial Key Laboratory of Animal Embryo Engineering, Jilin University, Changchun 130062, China.
Yuxin ZhangJilin Provincial Key Laboratory of Animal Embryo Engineering, Jilin University, Changchun 130062, China.
Bing YaoJilin Provincial Key Laboratory of Animal Embryo Engineering, Jilin University, Changchun 130062, China.
Nannan LiJilin Provincial Key Laboratory of Animal Embryo Engineering, Jilin University, Changchun 130062, China.
Liangxue LaiJilin Provincial Key Laboratory of Animal Embryo Engineering, Jilin University, Changchun 130062, China.
Zhanjun LiJilin Provincial Key Laboratory of Animal Embryo Engineering, Jilin University, Changchun 130062, China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hair growth and morphology are generally regulated by the hair cycle in mammals. Fibroblast Growth Factor 5 (FGF5), which is a hair cycle regulator, has a role in regulating the hair cycle during the transition from the anagen phase to the catagen phase, and a hereditary long hair phenotype has been widely reported when

Indexed as

AnimalsCRISPR-Cas SystemsExonsFibroblast Growth Factor 5HairHair FolliclePhenotypeRabbitsRNA, MessengerFibroblast Growth Factor 5RNA, MessengerFGF5hair cyclelong hairrabbit

Identifiers

PMID32168764
PMCPMC7140871
OpenAlexW3011352313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.