Evidence map›Paper›PMID 32168729›Full record

ArticleNutrients2020

α-Linolenic Acid-Rich Diet Influences Microbiota Composition and Villus Morphology of the Mouse Small Intestine.

Hristo Todorov, Bettina Kollar, Franziska Bayer, Inês Brandão, Amrit Mann, Julia Mohr, Giulia Pontarollo, Henning Formes, Roland Stauber, Jens M Kittner and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

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  16. Prevalence of an Intestinal ST40International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Hristo TodorovInstitute for Developmental Biology and Neurobiology, Faculty of Biology and Center for Computational Sciences in Mainz, Johannes Gutenberg-University Mainz, Staudingerweg 9, 55128 Mainz, Germany; .ORCID 0000-0003-2734-7701
Bettina KollarCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.
Franziska BayerCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.
Inês BrandãoCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.ORCID 0000-0003-3767-9515
Amrit MannCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.
Julia MohrCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.
Giulia PontarolloCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.
Henning FormesCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.
Roland StauberNanobiomedicine, University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.
Jens M KittnerMedical Department 2 (Gastroenterology, Hepatology, Pneumology, Endocrinology) Klinikum Darmstadt GmbH, Grafenstr. 9, 64283 Darmstadt, Germany.
Kristina EndresDepartment of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Bernhard WatzerMetabolomics Core Facility, Philipps-University, 35043 Marburg, Germany.
Wolfgang Andreas NockherInstitute of Laboratory Medicine and Pathobiochemistry, Philipps-University, 35043 Marburg, Germany.
Felix SommerInstitute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, 24105 Kiel, Germany.ORCID 0000-0002-6545-3487
Susanne GerberInstitute for Developmental Biology and Neurobiology, Faculty of Biology and Center for Computational Sciences in Mainz, Johannes Gutenberg-University Mainz, Staudingerweg 9, 55128 Mainz, Germany; .
Christoph ReinhardtCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.ORCID 0000-0002-0696-2636
Johannes Gutenberg University Mainz · DEPhilipps University of Marburg · DEChristian-Albrechts-Universität zu Kiel · DEKlinikum Darmstadt · DEPolytechnic Institute of Castelo Branco · PT

Funding

Boehringer Ingelheim Stiftung Novel and neglected cardiovascular risk factorsBundesministerium für Bildung und Forschung 01EO1003 and 01EO1503Deutsche Forschungsgemeinschaft RE 3450/5-2Inneruniversitäre Forschungsförderung (Stufe 1) -Naturwissenschaftlich-Medizinische Forschungszentrum (NMFZ) -
6 · The paper itself

Abstract

α-Linolenic acid (ALA) is well-known for its anti-inflammatory activity. In contrast, the influence of an ALA-rich diet on intestinal microbiota composition and its impact on small intestine morphology are not fully understood. In the current study, we kept adult C57BL/6J mice for 4 weeks on an ALA-rich or control diet. Characterization of the microbial composition of the small intestine revealed that the ALA diet was associated with an enrichment in

Indexed as

Animal FeedBiodiversityGastrointestinal Microbiomealpha-Linolenic AcidAnimalsFatty AcidsFecesFood AnalysisImmunohistochemistryIntestinal MucosaIntestine, SmallLipid MetabolismMaleMetagenomeMetagenomicsMicealpha-Linolenic AcidFatty Acidsepithelial renewalgoblet cellsmicrobiotaPaneth cellsvillus morphologyα-linolenic acid

Identifiers

PMID32168729
PMCPMC7146139
OpenAlexW3011647422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.