Evidence map›Paper›PMID 32168727›Full record

ArticleInternational journal of environmental research and public health2020

Biological Monitoring of Occupational Exposure to Metals in Electric Steel Foundry Workers and Its Contribution to 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine Levels.

Laura Campo, Mariem Hanchi, Sabrina Sucato, Dario Consonni, Elisa Polledri, Luca Olgiati, Dalila Saidane-Mosbahi, Silvia Fustinoni

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura CampoFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Mariem HanchiLaboratory of Analysis, Treatment and Recovery of Environmental Pollutants and Products, Faculty of Pharmacy, 5000 Monastir, Tunisia.
Sabrina SucatoDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.
Dario ConsonniFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-8935-3843
Elisa PolledriDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-9625-3656
Luca OlgiatiFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Dalila Saidane-MosbahiLaboratory of Analysis, Treatment and Recovery of Environmental Pollutants and Products, Faculty of Pharmacy, 5000 Monastir, Tunisia.
Silvia FustinoniFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-0287-7338

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the urinary concentrations of selected metals in workers from an electric steel foundry in Tunisia were assessed and compared with existing biological limit values and general population reference values. Moreover, the association between oxidative DNA damage, measured as urinary 8-oxo-7,8-dihydro-2'deoxyguanosine (8-oxodG) and co-exposure to metals and polycyclic aromatic hydrocarbons (PAHs) was evaluated. Urinary levels of 12 metals were determined by inductively coupled plasma-mass spectrometry (ICP-MS) in end-shift spot samples from 89 workers. The urinary levels of phenanthrene (U-PHE), as marker of exposure to PAHs, and 8-oxodG were also available. Median levels ranged from 0.4 µg/L (cobalt, Co, and thallium, Tl) to 895 µg/L (zinc, Zn). Only 1% of samples was above the biological limit values for Co, and up to 13.5% of samples were above limit values for Cd. From 3.4% (Co) to 72% (lead, Pb) of samples were above the reference values for the general population. Multiple linear regression models, showed that manganese (Mn), Zn, arsenic (As), barium (Ba), Tl, and Pb were significant predictors of 8-oxodG (0.012 ≤

Indexed as

Biological MonitoringOccupational Exposure8-Hydroxy-2'-DeoxyguanosineHumansMetallurgyMetals, HeavyPolycyclic Aromatic HydrocarbonsSteelTunisia8-Hydroxy-2'-DeoxyguanosineMetals, HeavyPolycyclic Aromatic HydrocarbonsSteel8-oxo-7,8-dihydro-2′-deoxyguanosinebiological limit valuesbiological monitoringelectric steel foundrymetalsoccupational exposurepolycyclic aromatic hydrocarbonsurine

Identifiers

PMID32168727
PMCPMC7142962

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.