Evidence map›Paper›PMID 32168532›Full record

ArticleEuropean journal of dentistry2020

Tea Tree Oil versus Chlorhexidine Mouthwash in Treatment of Gingivitis: A Pilot Randomized, Double Blinded Clinical Trial.

Francesca Ripari, Alessia Cera, Monica Freda, Giulia Zumbo, Francesca Zara, Iole Vozza

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Efficacy and safety ofFrontiers in pharmacology · 2023
    Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Review
  8. Nano-Enabled Advances in Tea Tree Essential Oil (Materials (Basel, Switzerland) · 2026
    Review
  9. Evaluation of the antimicrobial potential of fluoride-free mouthwashes against Scardovia wiggsiae.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Mouthwashes: Alternatives and Future Directions.International dental journal · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Francesca RipariDepartment of Oral and Maxillo facial Sciences, Sapienza University of Rome, Rome, Italy.
Alessia CeraDepartment of Oral and Maxillo facial Sciences, Sapienza University of Rome, Rome, Italy.
Monica FredaDepartment of Oral and Maxillo facial Sciences, Sapienza University of Rome, Rome, Italy.
Giulia ZumboDepartment of Oral and Maxillo facial Sciences, Sapienza University of Rome, Rome, Italy.
Francesca ZaraDepartment of Oral and Maxillo facial Sciences, Sapienza University of Rome, Rome, Italy.
Iole VozzaDepartment of Oral and Maxillo facial Sciences, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe study evaluated the efficacy of tea tree oil for the treatment of gingivitis. MATERIALS AND

methodsThe tea tree oil was administered in the form of mouthwash and then compared with a mouthwash with chlorhexidine 0.12%. Both treatments were domestic and lasted for 14 days. Patients were chosen according to random criteria, aged between 18 and 60 years, and who showed a clinically evident gingivitis. In clinical evaluation, the following clinical criteria were taken into consideration: gingival index (GI), plaque index (PI), bleeding index (BI), probing depth (PD), the presence of dental dyschromia, and the presence of taste alteration. The subjects were evaluated before (T0) and after the treatment (T1), and the data collected for each patient were recorded on a periodontal chart.

resultsThe comparison showed that tea tree oil offered a better improvement in the evaluation of PI, BOP, and PD; furthermore, it did not cause dental dyschromia and taste alteration. In group A, treated with tea tree oil, PI decreased from 53.25 to 5.50% and BI from 38.41 to 4.22%. In group B, treated with chlorhexidine PI decreased from 47.69 to 2.37% and BI from 32.93 to 6.28%. Instead, the subjects using chlorhexidine 0.12% blamed a distaste for the product that caused a slight taste alteration; 20% of them showed iatrogenic dental dyschromia.

conclusionsThe collected data showed the efficacy of both treatments. Although further research works will be necessary, this study showed that tea tree oil could be an effective nontoxic substitute for the therapy of gingivitis.

Identifiers

PMID32168532
PMCPMC7069753
OpenAlexW3011453493

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.