Evidence map›Paper›PMID 32168407›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Extending the Sensitivity of CEST NMR Spectroscopy to Micro-to-Millisecond Dynamics in Nucleic Acids Using High-Power Radio-Frequency Fields.

Atul Rangadurai, Honglue Shi, Hashim M Al-Hashimi

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Direct Measurement of 8OGbioRxiv : the preprint server for biology · 2024
    Article
  7. Article
  8. Identifying and Overcoming Artifacts inJournal of the American Chemical Society · 2023
    Article
  9. Article
  10. Review
  11. The A39G FF domain folds on a volcano-shaped free energy surface via separate pathways.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Review
  13. A quantitative model predicts how mNature communications · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Atul RangaduraiDepartment of Biochemistry, Duke University, 229, Nanaline Duke Building, 307 Research Drive, Durham, NC, 27710, USA.ORCID 0000-0003-2019-313X
Honglue ShiDepartment of Chemistry, Duke University, Durham, NC, 27708, USA.ORCID 0000-0003-3847-1652
Hashim M Al-HashimiDepartment of Biochemistry, Duke University, 229, Nanaline Duke Building, 307 Research Drive, Durham, NC, 27710, USA.ORCID 0000-0003-0681-1747

Funding

Role of DNA structural dynamics in mutagenesis and oncogenesisR01GM089846 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Hashim M Al-Hashimi · 2010 to 2026
$5.2M
Fundamental Studies of RNA Conformational ThermodynamicsR01GM132899 · NIGMS · STANFORD UNIVERSITY · PI AL-HASHIMI, HASHIM M, HERSCHLAG, DANIEL · 2019 to 2022
$2.7M
NIGMS NIH HHS R01 GM089846NIGMS NIH HHS R01GM089846NIGMS NIH HHS R01 GM132899NIGMS NIH HHS R01GM132899
6 · The paper itself

Abstract

Biomolecules undergo motions on the micro-to-millisecond timescale to adopt low-populated transient states that play important roles in folding, recognition, and catalysis. NMR techniques, such as Carr-Purcell-Meiboom-Gill (CPMG), chemical exchange saturation transfer (CEST), and R

Indexed as

Radio WavesDNALimit of DetectionMagnetic Resonance SpectroscopyMotionDNAbiophysicschemical exchange saturation transferDNA structuresnucleic acidsstructural dynamics

Identifiers

PMID32168407
PMCPMC7857695

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.