Evidence map›Paper›PMID 32168356›Full record

ArticlePloS one2020

Awareness of HIV-positive status and linkage to treatment prior to pregnancy in the "test and treat" era: A national antenatal sentinel survey, 2017, South Africa.

Selamawit Woldesenbet, Tendesayi Kufa, Mireille Cheyip, Kassahun Ayalew, Carl Lombard, Samuel Manda, Patrick Nadol, Peter Barron, Brian Chirombo, Ehi Igumbor and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Selamawit WoldesenbetCenter for HIV and STI, National Institute for Communicable Diseases, Johannesburg, South Africa.ORCID 0000-0002-5023-3561
Tendesayi KufaCenter for HIV and STI, National Institute for Communicable Diseases, Johannesburg, South Africa.
Mireille CheyipStrategic Information Unit, Center for Disease Control and Prevention, Pretoria, South Africa.
Kassahun AyalewStrategic Information Unit, Center for Disease Control and Prevention, Pretoria, South Africa.
Carl LombardBiostatistics Unit, South African Medical Research Council, Cape Town, South Africa.ORCID 0000-0002-2136-6533
Samuel MandaBiostatistics Unit, South African Medical Research Council, Pretoria, South Africa.
Patrick NadolStrategic Information Unit, Center for Disease Control and Prevention, Pretoria, South Africa.
Peter BarronSchool of Public Health, University of the Witwatersrand, Johannesburg, South Africa.
Brian ChiromboHIV and Hepatitis Program, World Health Organization, Pretoria, South Africa.
Ehi IgumborStrategic Information Unit, Center for Disease Control and Prevention, Pretoria, South Africa.
Yogan PillayHIV & AIDS, TB and Maternal, Child and Women's Health (MCWH), National Department of Health, Pretoria, South Africa.
Adrian PurenCenter for HIV and STI, National Institute for Communicable Diseases, Johannesburg, South Africa.
University of Pretoria · ZAUniversity of the Witwatersrand · ZASouth African Medical Research Council · ZADepartment of Health · ZA

Funding

PEPFARWorld Health Organization 001
6 · The paper itself

Abstract

introductionKnowledge of HIV status in South Africa (SA) is reported to be 90% among people living with HIV. National level estimates could mask population-specific levels, which are critical to monitor program coverage and potential impact. Using data from the 2017 national antenatal sentinel survey, we assessed knowledge of HIV-positive status, initiation of antiretroviral therapy (ART), and socio-demographic characteristics associated with knowledge of HIV-positive status prior to the current pregnancy among women attending antenatal care.

methodsBetween 1 October and 15 November 2017, a nationally representative sample of 32,716 pregnant women were enrolled from 1,595 public health facilities selected from all districts of SA. Data on age, gravidity, knowledge of HIV-positive status and ART initiation prior to pregnancy were extracted from medical records. A blood sample was collected from each woman regardless of prior knowledge of HIV status or ART history, and tested for HIV in the laboratory. All HIV-positive pregnant women enrolled in the survey were eligible for inclusion in the analysis. Multivariable survey logistic regression was used to examine factors associated with knowledge of HIV-positive status prior to the current pregnancy.

resultsOf 10,065 eligible HIV-positive women, 60.8% (95% confidence interval (CI):59.9%-61.7%) knew their HIV status prior to the current pregnancy, of whom 91.1% (95% CI: 90.4%-91.7%) initiated ART prior to the current pregnancy. Knowledge of HIV-positive status was lower among adolescent girls and young women (15-24 years) (38.9%) and primigravid women (40.5%) compared with older women (35-49 years) (75.5%) and multigravid women (64.7%). In a multivariable analysis, significant effect modification was found between gravidity and age (P value = 0.047). Being in the age group 15-24 years compared to the age group 35-49 years decreased the odds of knowing HIV-positive status by 80% (adjusted odds ratio (AOR): 0.2, 95% CI:0.1-0.4) among primigravid women and by 60%(AOR: 0.4, 95% CI:0.3-0.4) among multigravid women.

conclusionKnowledge of HIV-positive status prior to the current pregnancy fell short of the target of 90% among pregnant women living with HIV. This was especially low among adolescent girls and young women, highlighting the gap in youth friendly reproductive health and HIV testing services.

Indexed as

Health Knowledge, Attitudes, PracticeInfectious Disease Transmission, VerticalAdolescentAdultAntiretroviral Therapy, Highly ActiveFemaleHIVHIV InfectionsHumansMass ScreeningMiddle AgedPregnancyPregnancy Complications, InfectiousSouth AfricaUrban PopulationYoung Adult

Identifiers

PMID32168356
PMCPMC7069609
OpenAlexW3011845650

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.