GuidelineObstetrics and gynecology2020
Diagnosis and Management of Adenocarcinoma in Situ: A Society of Gynecologic Oncology Evidence-Based Review and Recommendations.
Guideline in Obstetrics and gynecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05267834 (In Situ/Microinvasive Adenocarcinoma of the Uterine Cervix and HPV-type Impact), which is not on this map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
In Situ/Microinvasive Adenocarcinoma of the Uterine Cervix and HPV-type Impact: Pathologic Features, Treatment Options, and Follow-up Outcomes - Cervical Adenocarcinoma Study Group (CAS-Group).
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- 2019 ASCCP Risk-Based Management Consensus Guidelines for Abnormal Cervical Cancer Screening Tests and Cancer Precursors.Journal of lower genital tract disease · 2020Guideline
- Review
- Review
- Cold-knife conization versus loop electrosurgical excision for cervical adenocarcinoma in situ: a retrospective cohort study.BMC women's health · 2026Article
- Global Comparative Review of Guidelines for Cervical Adenocarcinoma In Situ.Life (Basel, Switzerland) · 2026Review
- Early Cancer Detection: What's Going on and What's Next.MedComm · 2026Review
- Relationship Between GLIM-Defined Malnutrition and Postoperative Outcomes After Curative Resection in Patients With Gastroenterological Cancer: Update Systematic Review and Meta-Analysis.Annals of gastroenterological surgery · 2026Review
- Cervical Adenocarcinoma In Situ in Young Nulliparous Patient with Persistent ASC-US and Multiple-Type HPV Infections Without HPV 16 and 18 Types-Case Report.Diagnostics (Basel, Switzerland) · 2026Article
- Occult cervical large cell neuroendocrine carcinoma masquerading as adenocarcinoma in situ during pregnancy: a case report, literature review, and SEER analysis.BMC pregnancy and childbirth · 2026Review
- Pathological outcomes in women with cervical adenocarcinomaFrontiers in oncology · 2026Article
- Association between cervical conization and pregnancy outcomes: A nationwide population-based cohort study.PloS one · 2026Article
- Article
- Review
- Article
- Nationwide cohort study on the risk of high-grade cervical dysplasia and carcinoma after conservative treatment or hysterectomy for adenocarcinoma in situ.International journal of cancer · 2025Article
- Analysis of precancerous lesion-related microRNAs for early diagnosis of cervical cancer in the Thai population.Scientific reports · 2025Article
- Risk factors associated with adverse outcomes after cervical conization in patients with cervical adenocarcinoma in situ.PloS one · 2025Article
- Evaluating PAX1/JAM3 methylation for triage in HPV 16/18-infected women.Clinical epigenetics · 2024Article
- Contemporary Review of Adenocarcinoma of the Cervix.Current treatment options in oncology · 2024Review
- ECC at LLETZ-An Exploratory Retrospective Cohort Study.Journal of clinical medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This publication represents an extensive literature review with the goal of providing guidelines for the evaluation and management of cervical adenocarcinoma in situ (AIS). The authors drafted the guidelines on behalf of the Society of Gynecologic Oncology, and the guidelines have been reviewed and endorsed by the ASCCP. These guidelines harmonize with the ASCCP Risk-Based Management Consensus Guidelines and provide more specific guidance beyond that provided by the ASCCP guidelines. Examples of updates include recommendations to optimize the diagnostic excisional specimen, AIS management in the setting of positive compared with negative margins on the excisional specimen, surveillance and definitive management after fertility-sparing treatment, and management of AIS in pregnancy. The increasing incidence of AIS, its association with human papillomavirus-18 infection, challenges in diagnosis owing to frequent origin within the endocervical canal, and the possibility of skip lesions all make AIS a unique diagnosis whose management needs to be differentiated from the management of the more prevalent squamous cell dysplasia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.