ArticleClinical orthopaedics and related research2020
Projections of Primary TKA and THA in Germany From 2016 Through 2040.
Article in Clinical orthopaedics and related research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 129 papers, 8 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Repeat Dose Steroid to Prevent Pain Relapse After Total Knee Arthroplasty in Patients With High Pain Response - A Randomized Double-blind Placebo-controlled Trial
The Effect of Cryoneurolysis for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty in High Pain Responders - A Randomized, Participant- and Observer-masked, Sham-controlled Trial
Can Preoperative Information Via Virtual Reality Affect Patient's Anxiety? A Randomized Controlled Trial and Patient Interviews
Who cites it
129 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Smart device-assisted telerehabilitation versus conventional rehabilitation after total nee arthroplasty: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Clinical prediction models for postoperative blood transfusion after total knee arthroplasty: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- What proportion of people have long-term pain after total hip or knee replacement? An update of a systematic review and meta-analysis.BMJ open · 2025Pooled it
- Association between malnutrition status and total joint arthroplasty periprosthetic joint infection and surgical site infection: a systematic review meta-analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- Incidence of periprosthetic joint infection after primary total knee arthroplasty shows significant variation : a synthesis of meta-analysis and bibliometric analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- Novel diagnostic markers for periprosthetic joint infection: a systematic review.Frontiers in cellular and infection microbiology · 2023Pooled it
- A comparison of functional outcomes following inpatient versus outpatient hip or knee arthroplasty.Journal of orthopaedic surgery and research · 2022Pooled it
- Can minimal clinically important differences in patient reported outcome measures be predicted by machine learning in patients with total knee or hip arthroplasty? A systematic review.BMC medical informatics and decision making · 2022Pooled it
- The Analgesic Effect of Low-Dose S(+)-Ketamine in Knee Joint Replacement: A Randomized Controlled Trial.Journal of pain research · 2025Trial
- Unilateral Strength Training after Total Knee Arthroplasty Leads to Similar or Better Effects on Strength and Flexibility than Bilateral Strength Training - A Randomized Controlled Pilot Study.Journal of rehabilitation medicine · 2023Trial
- Effect of dexamethasone as an analgesic adjuvant to multimodal pain treatment after total knee arthroplasty: randomised clinical trial.BMJ (Clinical research ed.) · 2022Trial
- High-dose steroids in high pain responders undergoing total knee arthroplasty: a randomised double-blind trial.British journal of anaesthesia · 2022Trial
- Clinical outcomes and patient-reported joint noise after total knee arthroplasty using saddle-shaped rotating-platform and bi-cruciate-stabilized implant-surgical systems: a propensity score-matched cohort study.Arthroplasty (London, England) · 2026Article
- Cumulative revision rates in total hip arthroplasty depending on acetabular cup fixation: an analysis from the German arthroplasty registry.Arthroplasty (London, England) · 2026Article
- Preferences for postoperative exercise in patients after total hip or knee arthroplasty: a discrete choice experiment.BMC health services research · 2026Article
- Diverging trends in primary and revision arthroplasty in Germany: projections and implications for healthcare delivery for the next ten years.International orthopaedics · 2026Article
- Safety of posterolateral approach with a polished cemented stem and a modular dual mobility implant in patients over 75 years old.Journal of orthopaedics · 2026Article
- Coordinated Return-to-Work model reduces sickness absences after hip or knee arthroplasty: a registry-based study.Archives of orthopaedic and trauma surgery · 2026Article
- Comparing Anterior Versus Posterior Size Referencing in Patients Undergoing Simultaneous Bilateral Total Knee Arthroplasty: One Technique Per Knee.Indian journal of orthopaedics · 2026Article
- Can virtual consultations replace physical visits before knee arthroplasty? : a retrospective cohort study.Bone & joint open · 2026Article
69 more citing papers are in PubMed but not listed here.
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4 authors.
Funding
Abstract
backgroundFuture projections for both TKA and THA in the United States and other countries forecast a further increase of already high numbers of joint replacements. The consensus is that in industrialized countries, this increase is driven by demographic changes with more elderly people being less willing to accept activity limitations. Unlike the United States, Germany and many other countries face a population decline driven by low fertility rates, longer life expectancy, and immigration rates that cannot compensate for population aging. Many developing countries are likely to follow that example in the short or medium term amid global aging. Due to growing healthcare expenditures in a declining and aging population with a smaller available work force, reliable predictions of procedure volume by age groups are requisite for health and fiscal policy makers to maintain high standards in arthroplasty for the future population.Questions/purposes (1) By how much is the usage of primary TKA and THA in Germany expected to increase from 2016 through 2040? (2) How is arthroplasty usage in Germany expected to vary as a function of patient age during this time span?
methodsThe annual number of primary TKAs and THAs were calculated based on population projections and estimates of future healthcare expenditures as a percent of the gross domestic product (GDP) in Germany. For this purpose, a Poisson regression analysis using age, gender, state, healthcare expenditure, and calendar year as covariates was performed. The dependent variable was the historical number of primary TKAs and THAs performed as compiled by the German federal office of statistics for the years 2005 through 2016.
resultsThrough 2040, the incidence rate for both TKA and THA will continue to increase annually. For TKA, the incidence rate is expected to increase from 245 TKAs per 100,000 inhabitants to 379 (297-484) (55%, 95% CI 21 to 98). The incidence rate of THAs is anticipated to increase from 338 to 437 (357-535) per 100,000 inhabitants (29% [95% CI 6 to 58]) between 2016 and 2040. The total number of TKAs is expected to increase by 45% (95% CI 14 to 8), from 168,772 procedures in 2016 to 244,714 (95% CI 191,920 to 312,551) in 2040. During the same period, the number of primary THAs is expected to increase by 23% (95% CI 0 to 50), from 229,726 to 282,034 (95% CI 230,473 to 345,228). Through 2040, the greatest increase in TKAs is predicted to occur in patients aged 40 to 69 years (40- to 49-year-old patients: 269% (95% CI 179 to 390); 50- to 59-year-old patients: 94% (95% CI 48 to 141); 60- to 69-year-old patients: 43% (95% CI 13 to 82). The largest increase in THAs is expected in the elderly (80- to 89-year-old patients (71% [95% CI 40 to 110]).
conclusionsAlthough the total number of TKAs and THAs is projected to increase in Germany between now and 2040, the increase will be smaller than that previously forecast for the United States, due in large part to the German population decreasing over that time, while the American population increases. Much of the projected increase in Germany will be from the use of TKA in younger patients and from the use of THA in elderly patients. Knowledge of these trends may help planning by surgeons, hospitals, stakeholders, and policy makers in countries similar to Germany, where high incidence rates of arthroplasty, aging populations, and overall decreasing populations are present. LEVEL OF EVIDENCE: Level III, economic and decision analysis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.