ArticleAmerican journal of physiology. Heart and circulatory physiology2020
Flow profile characteristics in Fontan circulation are associated with the single ventricle dilation and function: principal component analysis study.
Article in American journal of physiology. Heart and circulatory physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
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Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- After the Lateral Tunnel Fontan, the Intra-Atrial Channel Grows and Remains Phasic, Expanding in Systole.Pediatric cardiology · 2026Article
- Deep learning for vessel segmentation and flow analysis to identify clusters associated with adverse outcomes in a fontan patient registry.Scientific reports · 2026Article
- Central Venous Waveform Patterns in the Fontan Circulation Independently Contribute to the Prediction of Composite Survival.Pediatric cardiology · 2024Review
- Application of Principal Component Analysis to Heterogenous Fontan Registry Data Identifies Independent Contributing Factors to Decline.medRxiv : the preprint server for health sciences · 2024Article
- Extraction and Digitization of ECG Signals from Standard Clinical Portable Document Format Files for the Principal Component Analysis of T-wave Morphology.Cardiovascular engineering and technology · 2023Article
- Myocardial strain-curve deformation patterns after Fontan operation.Scientific reports · 2023Article
- Coupled waveform patterns in the arterial and venous fontan circulation are related to parameters of pulmonary, lymphatic and cardiac function.International journal of cardiology. Congenital heart disease · 2023Article
- The Influence of Respiration on Blood Flow in the Fontan Circulation: Insights for Imaging-Based Clinical Evaluation of the Total Cavopulmonary Connection.Frontiers in cardiovascular medicine · 2021Review
- Prediction of Fluid Responsiveness by Stroke Volume Variation in Children Undergoing Fontan Operation.BioMed research international · 2020Article
- Normal and adverse pulmonary arterial flow patterns after the Fontan procedure and correlation with invasive CMR (iCMR) hemodynamics: A retrospective observational study.JRSM cardiovascular diseaseArticle
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
Abstract
The Fontan circulation is characterized as a nonpulsatile flow propagation without a pressure-generating ventricle. However, flow through the Fontan circulation still exhibits oscillatory waves as a result of pressure changes generated by the systemic single ventricle. Identification of discrete flow patterns through the Fontan circuit may be important to understand single ventricle performance. Ninety-seven patients with Fontan circulation underwent phase-contrast MRI of the right pulmonary artery, yielding subject-specific flow waveforms. Principal component (PC) analysis was performed on preprocessed flow waveforms. Principal components were then correlated with standard MRI indices of function, volume, and aortopulmonary collateral flow. The first principal component (PC) described systolic versus diastolic-dominant flow through the Fontan circulation, accounting for 31.3% of the variance in all waveforms. The first PC correlated with end-diastolic volume (
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Registered trials
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