ArticleImmunity, inflammation and disease2020
Dose response of black American mink to Aleutian mink disease virus.
Article in Immunity, inflammation and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Pathogenesis of Aleutian Mink Disease Virus Infection-Comparison of Natural Transmission with Experimental Aerosol and Intraperitoneal Inoculation.Pathogens (Basel, Switzerland) · 2026Article
- Prevalence of Aleutian Mink Disease Virus (AMDV) in Free-Ranging American Mink from Biebrza and Narew National Parks (Poland)-An Epidemiological Concern.Animals : an open access journal from MDPI · 2024Article
- A developed TaqMan probe-based qPCR was used to quantify the distribution of AMDV in various tissues of infected mink and its prevalence in northern China.Frontiers in veterinary science · 2024Article
- Review
- Serum Analytes of American Mink (Neovison Vison) Challenged with Aleutian Mink Disease Virus.Animals : an open access journal from MDPI · 2022Article
- Long-term antibody production and viremia in American mink (Neovison vison) challenged with Aleutian mink disease virus.BMC veterinary research · 2022Article
- Phagocytic Activity, Oxygen Metabolism and Serum Amyloid a Concentration in Peripheral Blood of Mink with Subclinical Aleutian Virus Infection.Animals : an open access journal from MDPI · 2022Article
- AMDV Vaccine: Challenges and Perspectives.Viruses · 2021Review
- Detection of selection signatures for response to Aleutian mink disease virus infection in American mink.Scientific reports · 2021Article
- Dietary supplementation of Ascophylum nodosum improved kidney function of mink challenged with Aleutian mink disease virus.BMC veterinary research · 2020Article
- Dose response of black American mink to Aleutian mink disease virus.Immunity, inflammation and disease · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAleutian mink disease virus (AMDV) causes a serious health problem for mink globally. The disease has no cure nor an effective vaccine and selection for tolerance using antibody titer is adopted by many mink farmers. The objective of this study was to investigate the effects of various doses of a local AMDV isolate on the response of black American mink to infection with AMDV.
methodsEight black American mink were each inoculated intranasally with 0.5 mL of eight serial 10-fold dilutions (10
resultsAntibody production persisted in all seroconverted mink until the termination of the experiment, whereas 71.1% of the mink showed short-lived viremia. Significant associations were observed between inoculum dose and the incidence of viremia until 84 dpi which disappeared thereafter, whereas associations between inoculum dose and the incidence of seropositive mink were significant on all sampling occasions. Antibody titer at 218 dpi significantly decreased with decreasing inoculum dose. AMDV DNA was detected in the bone marrow, lymph nodes, and spleen samples of almost all mink inoculated at every dose but was not detected in other organs of some mink.
conclusionsCIEP is more accurate than PCR for detecting AMDV infection in mink. Using antibody titer in naturally infected mink may not be accurate for the identification of tolerant mink.
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