Evidence map›Paper›PMID 32167475›Full record

ArticleeLife2020

Global phenotypic profiling identifies a conserved actinobacterial cofactor for a bifunctional PBP-type cell wall synthase.

Joel W Sher, Hoong Chuin Lim, Thomas G Bernhardt

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. A broadly conserved gram-positive lipoprotein regulates cell elongation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Bacteriophages target membrane-anchored glycopolymers to promote host cell lysis and progeny release.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Transposon insertion site sequencing (TIS) of Pseudomonas aeruginosa.Journal of microbiology (Seoul, Korea) · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. High-Throughput Screen for Cell Wall Synthesis Network Module inFrontiers in bioengineering and biotechnology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Joel W SherDepartment of Microbiology, Harvard Medical School, Boston, United States.ORCID 0000-0002-0616-7632
Hoong Chuin LimDepartment of Microbiology, Harvard Medical School, Boston, United States.ORCID 0000-0001-8463-8375
Thomas G BernhardtDepartment of Microbiology, Harvard Medical School, Boston, United States.ORCID 0000-0003-3566-7756

Funding

Peptidoglycan Biogenesis in Escherichia ColiR01AI083365 · NIAID · HARVARD MEDICAL SCHOOL · PI Thomas G Bernhardt · 2010 to 2026
$8.3M
Bacteriology PhD Training ProgramT32AI132120 · NIAID · HARVARD MEDICAL SCHOOL · PI RUDNER, DAVID Z · 2017 to 2021
$1.7M
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI083365NIAID NIH HHS T32 AI132120
6 · The paper itself

Abstract

Members of the

Indexed as

Bacterial ProteinsCell WallCoenzymesConserved SequenceCorynebacterium glutamicumDNA Transposable ElementsGene Expression Regulation, BacterialTranscriptomeBacterial ProteinsCoenzymesDNA Transposable Elementscorynebacteriainfectious diseasemicrobiologymycobacteriapeptidoglycan

Identifiers

PMID32167475
PMCPMC7205459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.