Evidence map›Paper›PMID 32167428›Full record

SynthesisCurrent cardiology reviews2020

Management of Cardiogenic Shock due to Thyrotoxicosis: A Systematic Literature Review.

Milad Modarresi, Ahmed Amro, Mohammad Amro, Amal Sobeih, Uzo Okoro, Kanaan Mansoor, Carlos Rueda, Rawan Elhamdani, Nesreen BenHamed, Timothy Kocher and 1 more

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Current cardiology reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Thyroid and cardiovascular diseases.Turkish journal of medical sciences · 2024
    Review
  8. Review
  9. Thyrotoxic Cardiomyopathy: State of the Art.TouchREVIEWS in endocrinology · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Milad ModarresiDepartment of Cardiology/Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV-25755, United States.
Ahmed AmroSchool of Medicine. Misr University of Science and Technology, Cairo, United States.
Mohammad AmroDepartment of Cardiology/Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV-25755, Egypt.
Amal SobeihSchool of Medicine, AL-Najah University, Nablus, Palestinian Territory, Occupied.
Uzo OkoroDepartment of Cardiology/Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV-25755, United States.
Kanaan MansoorDepartment of Cardiology/Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV-25755, United States.
Carlos RuedaDepartment of Cardiology/Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV-25755, United States.
Rawan ElhamdaniDepartment of Cardiology/Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV-25755, United States.
Nesreen BenHamedDepartment of Cardiology/Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV-25755, United States.
Timothy KocherDepartment of Cardiology/Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV-25755, United States.
Mehiar ElhamdaniDepartment of Cardiology/Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV-25755, United States.
Marshall University · USAn-Najah National University · PS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA grave complication of thyrotoxicosis, or thyroid storm, is the development of heart failure and cardiomyopathy. Recognizing this condition is imperative in preventing further left ventricular dysfunction and cardiogenic shock. This manuscript aims to review the literature on cardiogenic shock associated with thyrotoxicosis and present management recommendations on this rare condition.

methodsA literature search was performed in December of 2018, using the PubMed medical search engine. A systematic search was carried out using the keywords Thyroid Storm AND Cardiogenic Shock and Thyrotoxicosis AND Shock. MANAGEMENT: Decrease of thyroid hormone levels using therapeutic plasma exchange LV Unloading and ventilation by Impella and Extracorporeal Mechanical Ventilation (ECMO).

conclusionPatients presenting with thyroid storm-induced shock may not be suitable candidates for traditional management with β -adrenergic blockers (β-blockers). The use of β-blockers could exasperate their condition. Through extensive literature review on this rare condition, the most effective management was found to be therapeutic plasma exchange in order to decrease thyroid hormone levels, which have direct toxic effect on the heart. Furthermore, the use of ECMO and Impella is advised to reduce pressure on the heart and ensure the patient's organs are well oxygenated and perfused while the left ventricle is recovering.

Indexed as

AdultAgedFemaleHumansMaleMiddle AgedShock, CardiogenicSurvival AnalysisThyrotoxicosiscardiogenic shockECMOimpellashocktherapeutic plasma exchangethyroid stormThyrotoxicosis

Identifiers

PMID32167428
PMCPMC7903499
OpenAlexW3011726712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.