Evidence map›Paper›PMID 32166985›Full record

ArticleDrug delivery2020

Ultrasound-responsive highly biocompatible nanodroplets loaded with doxorubicin for tumor imaging and treatment

Xiaoying Zhou, Lu Guo, Dandan Shi, Dong Meng, Xiao Sun, Mengmeng Shang, Xinxin Liu, Yading Zhao, Jie Li

Abstract read
In one paragraph

Article in Drug delivery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Harnessing Ultrasonic Technologies to TreatMolecules (Basel, Switzerland) · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Acoustic Nanodrops for Biomedical Applications.Current opinion in colloid & interface science · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaoying ZhouDepartment of Ultrasound, Qilu Hospital of Shandong University, Jinan, China.ORCID http://orcid.org/0000-0002-8329-4707
Lu GuoDepartment of Ultrasound, Qilu Hospital of Shandong University, Jinan, China.
Dandan ShiDepartment of Ultrasound, Qilu Hospital of Shandong University, Jinan, China.
Dong MengDepartment of Ultrasound, Qilu Hospital of Shandong University, Jinan, China.
Xiao SunDepartment of Ultrasound, Qilu Hospital of Shandong University, Jinan, China.
Mengmeng ShangDepartment of Ultrasound, Qilu Hospital of Shandong University, Jinan, China.
Xinxin LiuDepartment of Ultrasound, Qilu Hospital of Shandong University, Jinan, China.
Yading ZhaoDepartment of Ultrasound, Qilu Hospital of Shandong University, Jinan, China.
Jie LiDepartment of Ultrasound, Qilu Hospital of Shandong University, Jinan, China.ORCID http://orcid.org/0000-0001-6165-2668

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an injectable anticancer drug delivery system, the biological safety of nanocarriers is the most important prerequisite for their clinical application. The objective of our study was to synthesize special ultrasound-responsive highly biocompatible chitosan nanodroplets (BCNDs), observe their spatiotemporally control the delivery of doxorubicin (DOX)

Indexed as

Drug Delivery SystemsNanoparticlesUltrasonographyAnimalsAntibiotics, AntineoplasticCell Line, TumorChitosanDoxorubicinDrug CarriersMaleMiceMice, Inbred BALB CNeoplasmsAntibiotics, AntineoplasticChitosanDoxorubicinDrug Carrierschitosan nanodropletscontrast-enhanced ultrasound imagingdrug delivery systemHigh biocompatibilityspatiotemporally controlled delivery

Identifiers

PMID32166985
PMCPMC7144186

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.