Evidence map›Paper›PMID 32166867›Full record

ArticleMolecular genetics & genomic medicine2020

Haplotype diversity and phylogenetic characteristics for Guanzhong Han population from Northwest China via 38 Y-STRs using Yfiler™ Platinum Amplification System.

Luyao Li, Lilan Yao, Xin He, Huilin Gong, Yuan Deng, Mei Luan, Guanglin He, Fuquan Jia, Pengyu Chen

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Article in Molecular genetics & genomic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

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7citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Luyao LiDepartment of Pathology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID 0000-0003-1397-5045
Lilan YaoCenter of Forensic Expertise, Affiliated hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Xin HeDepartment of Mathematics, Sichuan University, Chengdu, Sichuan, China.
Huilin GongDepartment of Pathology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Yuan DengDepartment of Pathology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Mei LuanDepartment of Dermatology and Venerology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Guanglin HeInstitute of Forensic medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.ORCID 0000-0002-6614-5267
Fuquan JiaDepartment of Forensic Medicine, Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region, China.
Pengyu ChenCenter of Forensic Expertise, Affiliated hospital of Zunyi Medical University, Zunyi, Guizhou, China.ORCID 0000-0002-3706-103X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor better application in human forensic cases and population genetics research, it is imperative to investigate the genetic characteristics of Guanzhong Han population using enhanced Y-chromosomal short tandem repeats (Y-STR) detecting system with higher discriminating power than previous ones.

methodsIn this study, 38 Y-STRs were profiled in 430 unrelated Chinese Han male individuals from Guanzhong region of Shaanxi Province, Northwest China, using the Yfiler™ Platinum PCR Amplification Kit. Haplotype frequencies and forensic parameters were calculated. Comprehensive population comparisons with geographically/ethnically different populations in China and other worldwide countries were performed.

resultsA total of 422 different haplotypes were observed with the overall haplotype diversity (HD), discriminatory power (DC) and haplotype match probability (HMP) were 0.9999, 0.9814, and 0.0024, respectively. Guanzhong Han showed genetically affinity with Han ethnicity from Shanxi and Henan provinces, while far distant from Tibetan populations.

conclusionThis study offered a unique insight into Guanzhong Han population, the 38 Y-STRs included in the the Yfiler™ Platinum system are highly polymorphic and informative and can be used for forensic practice and human genetic research.

Indexed as

HaplotypesChinaChromosomes, Human, YEthnicityForensic GeneticsGenotyping TechniquesHumansMaleMicrosatellite RepeatsPhylogenyPolymorphism, GeneticPopulationforensic geneticsgenetic diversityGuanzhong Han populationY-chromosomal STRYfiler™ Platinum system

Identifiers

PMID32166867
PMCPMC7216798

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