Evidence map›Paper›PMID 32166765›Full record

ArticleGenetic epidemiology2020

The effects of misspecification of the mediator and outcome in mediation analysis.

Sharon M Lutz, Joanne E Sordillo, John E Hokanson, Ann Chen Wu, Christoph Lange

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetic epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Microbiology and postmortem interval: a systematic review.Forensic science, medicine, and pathology · 2024
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sharon M LutzDepartment of Population Medicine, PRecisiOn Medicine Translational Research Center, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.ORCID 0000-0002-1515-9431
Joanne E SordilloDepartment of Population Medicine, PRecisiOn Medicine Translational Research Center, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
John E HokansonDepartment of Epidemiology, University of Colorado, Boulder, Colorado.
Ann Chen WuDepartment of Population Medicine, PRecisiOn Medicine Translational Research Center, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Christoph LangeDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
Age-Dependent Pharmacogenomics of Asthma Treatment (ADAPT)R01HD085993 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI WU, ANN CHEN · 2016 to 2020
$3.1M
Preparing Association Analysis Software Tools for Next Generation Sequencing DataR01HG008976 · NHGRI · HARVARD SCHOOL OF PUBLIC HEALTH · PI LANGE, CHRISTOPH · 2016 to 2018
$1.1M
Common Genetic Pathways Underlying CVD and COPDK01HL125858 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI LUTZ, SHARON MARIE · 2015 to 2019
$721k
NHGRI NIH HHS R01 HG008976NHLBI NIH HHS K01 HL125858NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NICHD NIH HHS R01 HD085993
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID32166765
PMCPMC7205563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.