Evidence map›Paper›PMID 32166707›Full record

SynthesisNeuropsychology review2020

Inhibitory Control Deficits in Individuals with Amnestic Mild Cognitive Impairment: a Meta-Analysis.

Rahel Rabi, Brandon P Vasquez, Claude Alain, Lynn Hasher, Sylvie Belleville, Nicole D Anderson

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neuropsychology review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

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  6. Three-Year Changes in Cognitive and Brain Functions Among Community-Dwelling Older Adults Who Continue Working.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rahel RabiRotman Research Institute, Baycrest, Toronto, ON, Canada.
Brandon P VasquezNeuropsychology and Cognitive Health, Baycrest, Toronto, ON, Canada.
Claude AlainRotman Research Institute, Baycrest, Toronto, ON, Canada.
Lynn HasherRotman Research Institute, Baycrest, Toronto, ON, Canada.
Sylvie BellevilleResearch Center, Institut Universitaire de Gériatrie de Montréal, Canada and Université de Montréal, Montréal, Québec, Canada.
Nicole D AndersonRotman Research Institute, Baycrest, Toronto, ON, Canada. nanderson@research.baycrest.org.ORCID 0000-0002-5979-2220
University of Toronto · CABaycrest Hospital · CAInstitut Universitaire de Gériatrie de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amnestic mild cognitive impairment (aMCI) is a prodromal stage of Alzheimer's disease that is characterized by impairments in episodic memory. Recent evidence has shown that inhibitory control is also impaired in aMCI. The aim of the present meta-analysis was to quantify inhibitory control ability in individuals with aMCI by examining performance across a range of well-defined inhibition paradigms that tapped into one of three inhibitory control subtypes (i) interference control (e.g., Stroop task), (ii) response inhibition (e.g., Go/Nogo task), or (iii) inhibition of cognitive sets (Wisconsin Card Sort Task). Reference databases (PsychINFO, PubMed, and Web of Science) were searched for studies comparing individuals with aMCI to healthy controls on behavioural measures of inhibition. Across 70 effect sizes involving 2184 adults with aMCI and 3049 controls, overall inhibition deficits of moderate magnitude (g = -0.73) were found among individuals with aMCI. Inhibition deficits were moderate in size regardless of inhibitory control subtype: interference control (g = -0.74), response inhibition (g = -0.71), inhibition of cognitive sets (g = -0.76). Subgroup analyses revealed that Stroop outcome measure (reaction time vs. accuracy) and recruitment source (clinical vs. community) moderated interference control deficits. Together these findings support a generalized inhibition deficit in aMCI, and suggest that inhibition tasks should be included routinely in neuropsychological test batteries to provide a more comprehensive overview of executive dysfunction in aMCI.

Indexed as

Inhibition, PsychologicalAmnesiaCognitive DysfunctionExecutive FunctionHumansNeuropsychological TestsCognitive testsInhibitory controlInterference controlMeta-analysisMild cognitive impairmentNeuropsychologyResponse inhibition

Identifiers

PMID32166707
OpenAlexW3011614712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.