Evidence map›Paper›PMID 32166569›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

Relationship between heart rate response and cardiac innervation in patients with suspected or known coronary artery disease.

Carmela Nappi, Roberta Assante, Emilia Zampella, Valeria Gaudieri, Giovanni De Simini, Alessia Giordano, Adriana D'Antonio, Wanda Acampa, Mario Petretta, Alberto Cuocolo

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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. European journal of nuclear medicine and molecular imaging · 2023
    Review
  3. Article
  4. Prognostic value of heart rate reserve in patients with suspected coronary artery disease undergoing stress myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Carmela NappiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Roberta AssanteDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Emilia ZampellaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Valeria GaudieriDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Giovanni De SiminiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Alessia GiordanoDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Adriana D'AntonioDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Wanda AcampaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Mario PetrettaDepartment of Translational Medical Sciences, University Federico II, Naples, Italy.
Alberto CuocoloDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy. cuocolo@unina.it.
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronotropic response to pharmacological stress test is blunted in patients with autonomic neuropathy. The relationship between heart rate (HR) changes during pharmacological stress test and cardiac autonomic dysfunction has not been fully investigated. We assessed the potential interplay between HR response (HRR) and myocardial innervation in patients with suspected or known coronary artery disease (CAD). METHODS AND

resultsWe studied 71 patients with suspected or known CAD referred to pharmacological stress myocardial perfusion imaging and

conclusionsThe relationship between HRR and cardiac sympathetic innervation in patients with suspected or known CAD confirms a strong interplay between cardiac response to stress tests and cardiac autonomic activation. This finding suggests that HRR may be used as a surrogate for assessing cardiac sympathetic function.

Indexed as

Heart RateAgedCoronary Artery DiseaseExercise TestFemaleHeartHumansMaleMiddle AgedCardiac innervationDiagnostic and prognostic applicationMPIVasodilators

Identifiers

PMID32166569
OpenAlexW3012195694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.