Evidence map›Paper›PMID 32166544›Full record

ArticleMedical oncology (Northwood, London, England)2020

The importance of subcapsular anesthesia in the anesthesiological management for thyroid radiofrequency ablation.

F Morelli, A M Ierardi, P Biondetti, S Zannoni, G Pompili, A Sacrini, A Coppola, G Rodà, S A Angileri, G Carrafiello

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

F MorelliDepartment of Radiology, San Paolo Hospital, Via A. Di Rudinì 8, 20142, Milan, Italy. francesco.morelli@unimi.it.ORCID http://orcid.org/0000-0002-1462-5787
A M IerardiDepartment of Radiology, San Paolo Hospital, Via A. Di Rudinì 8, 20142, Milan, Italy.
P BiondettiDepartment of Radiology, San Paolo Hospital, Via A. Di Rudinì 8, 20142, Milan, Italy.
S ZannoniDepartment of Radiology, San Paolo Hospital, Via A. Di Rudinì 8, 20142, Milan, Italy.
G PompiliDepartment of Radiology, San Paolo Hospital, Via A. Di Rudinì 8, 20142, Milan, Italy.
A SacriniDepartment of Radiology, San Paolo Hospital, Via A. Di Rudinì 8, 20142, Milan, Italy.
A CoppolaDepartment of Radiology, Università Degli Studi Dell'Insubria, Viale L. Borri 57, 21100, Varese, Italy.
G RodàDepartment of Radiology, San Paolo Hospital, Via A. Di Rudinì 8, 20142, Milan, Italy.
S A AngileriDepartment of Radiology, San Paolo Hospital, Via A. Di Rudinì 8, 20142, Milan, Italy.
G CarrafielloDepartment of Radiology, San Paolo Hospital, Via A. Di Rudinì 8, 20142, Milan, Italy.
Ospedale San Paolo · ITUniversity of Insubria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiofrequency ablation is a minimally invasive procedure alternative to surgery to treat benign thyroid nodules causing compressive symptoms. Tolerability of this procedure, aimed at treatment of benign conditions, is fundamental. In this study, we evaluated if local anesthesia should be enough to reduce both hospital costs and sedation-related risks for the patient, avoiding deep sedation and presence of the anesthesiologist. From July 2017 to August 2018, 14 consecutive patients (mean age 60.1 years) were treated and divided in two groups: Group A (7 patients) underwent systemic sedoanalgesia (intravenous remifentanil/fentanyl ± intravenous midazolam ± intravenous acetaminophen/nonsteroidal anti-inflammatory drugs) + subcutaneous anesthesia (lidocaine), with anesthesiologist. Group B (7 patients) underwent mild systemic sedoanalgesia (oral solution morphine sulfate + intravenous midazolam + intravenous acetaminophen) + both subcutaneous and subcapsular anesthesia (mepivacaine + bupivacaine), without anesthesiologist. Tolerability, sedation grade (Ramsay scale), total opioid dose, complications, and results at 12 months were analyzed and compared. Mean tolerability was 9.4 in group A and 8.9 in group B (p: 0.786). Mean sedation grade was 3.86 in group A and 2.71 in group B (p: 0.016). Mean total opioid dose was 70.9 mg in group A and 10 mg in group B (p:0.00015). No complications were observed. At 12 months, mean volume reduction was 56.1% in the group A and 60% in the group B. In thyroid radiofrequency ablation, subcapsular anesthesia can decrease both total opioid dose and level of patient's sedation without significant differences in tolerability, allowing to perform ablation without the anesthesiologist.

Indexed as

Radiofrequency AblationAdultAgedAged, 80 and overAnesthesiaAnesthesiologistsAnestheticsFemaleHumansMaleMiddle AgedMonitoring, IntraoperativeThyroid NoduleTreatment OutcomeAnestheticsAblative therapiesInterventional ultrasoundRadiofrequency ablationThyroid

Identifiers

PMID32166544
OpenAlexW3011837667

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.