ReviewJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2020
Left atrial appendage occlusion with the Amplatzer Amulet: update on device sizing.
Review in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Outcomes of Adding Computed Tomography Angiography for Pre-procedural Planning of Left Atrial Appendage Occlusion: a Systematic Review and Meta-analysis.Current cardiology reports · 2025Pooled it
- Comparative Study of Automated Real-Time Left Atrial Appendage Sizing Using Patient-Specific 3D Heart Models Versus Transesophageal Echocardiography and Multidetector Computed Tomography in Patients with Nonvalvular Atrial Fibrillation: Implications for Device Selection.Journal of clinical medicine · 2025Article
- Imaging assessment after percutaneous left atrial appendage closure: from immediate to long-term follow-up.European heart journal. Cardiovascular Imaging · 2025Review
- Percutaneous Left Atrial Appendage Closure: Supporting Evidence, Limitations and Future Directions.Journal of clinical medicine · 2025Review
- Preprocedural cardiac computed tomography versus transesophageal echocardiography for planning left atrial appendage occlusion procedures.Journal of cardiovascular imaging · 2024Review
- Computed tomography-based device-sizing in Amplatzer Amulet left atrial appendage occlusion.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Article
- Comparison of left atrial appendage measurements between conventional transesophageal echocardiography and "Virtual TEE" reconstructed from computed tomography for pre-procedural planning of device closure.Heart and vessels · 2024Article
- Measure twice, implant once.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Article
- Echocardiographic-Fluoroscopic Fusion Imaging Improves Interventionalists' Learning Curve for Percutaneous Left Atrial Appendage Closure-Initial, Single-Center, Retrospective Observations.Journal of cardiovascular development and disease · 2024Article
- MRI-based training model for left atrial appendage closure.International journal of computer assisted radiology and surgery · 2023Article
- Cardiac magnetic resonance imaging for preprocedural planning of percutaneous left atrial appendage closure.Frontiers in cardiovascular medicine · 2023Article
- Safety and feasibility of left atrial appendage inversion in swine: A proof-of-concept study for potential therapy to prevent embolic stroke.Frontiers in bioengineering and biotechnology · 2023Article
- Use of FEops artificial intelligence enabled technology for preprocedural planning of left atrial appendage occlusion with Amulet Amplatzer device.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2022Article
- Design and Rationale of the Swiss-Apero Randomized Clinical Trial: Comparison of Amplatzer Amulet vs Watchman Device in Patients Undergoing Left Atrial Appendage Closure.Journal of cardiovascular translational research · 2021Article
- Pulmonary ridge coverage and device-related thrombosis after left atrial appendage occlusion.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021Article
- Clinical Impact of Preprocedural CT-Based 3D Computational Simulation of Left Atrial Appendage Occlusion with Amulet.Journal of interventional cardiology · 2021Article
- Left atrial appendage occlusion in COVID-19 times.European heart journal supplements : journal of the European Society of Cardiology · 2020Article
- Why Follow-up Examinations After Left Atrial Appendage Closure Are Important: Detection of Complications During Follow-up and How to Deal with Them.Current cardiology reports · 2020Review
Corrections and comments
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Authors and funding
8 authors at 7 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present paper analyzes the role of different imaging modalities for left atrial appendage (LAA) assessment and the recommended specific measurements to improve device selection with regard to the Amulet device.
backgroundMorphological LAA assessment is one of the pivotal factors to achieve proper LAA sealing and potentially reduce the risk of complications by minimizing manipulation inside the appendage.
methodsEight experienced physicians in LAAO were asked to contribute in the preparation of a device sizing consensus manuscript after comprehensive assessment of previous published data on LAA imaging/measurement.
resultsLAA morphology is often complex and requires more detailed spatial resolution and 3-dimensional assessments to reduce the risk of mis-sizing. Traditionally, upsizing of devices based upon the largest measured LAA diameters have been used. However, this may lead to oversizing in markedly elliptical appendages. Thus, when 3D imaging modalities are available, utilizing the LAA mean diameters might be a better alternative. Operators should also note the systematic biases in differences in measurements obtained with different imaging modalities, with CT giving the largest measurements, followed by 3D-TEE, and then 2D-TEE and angiography. In fact, for 2D imaging techniques (2D-TEE and angiography), LAA diameters tend to be underestimated, and therefore, LAA largest diameters seem to be still the best option for device sizing. Some specific anatomies such as proximal chicken-wing or conic LAAs may require different measurements and implantations to achieve implant success.
conclusionsIn conclusion, LAA mean diameters might be a better alternative to largest diameters when 3D imaging modalities are available.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.