Evidence map›Paper›PMID 32166474›Full record

ReviewCurrent urology reports2020

Urinary microRNAs: Looking for a New Tool in Diagnosis, Prognosis, and Monitoring of Renal Cancer.

Julia Oto, Emma Plana, José Vicente Sánchez-González, Jorge García-Olaverri, Álvaro Fernández-Pardo, Francisco España, Manuel Martínez-Sarmiento, César D Vera-Donoso, Silvia Navarro, Pilar Medina

Open access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in Current urology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
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  6. Biomarkers in renal cell carcinoma and their targeted therapies: a review.Exploration of targeted anti-tumor therapy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Julia OtoHaemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute of Hospital La Fe, Fernando Abril Martorell 106, 46026, Valencia, Spain.
Emma PlanaHaemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute of Hospital La Fe, Fernando Abril Martorell 106, 46026, Valencia, Spain.
José Vicente Sánchez-GonzálezDepartment of Urology, La Fe Hospital, Fernando Abril Martorell 106, 46026, Valencia, Spain.
Jorge García-OlaverriDepartment of Urology, Hospital de Cruces, Baracaldo, Plaza de Cruces, S/N, 48903, Baracaldo, Vizcaya, Spain.
Álvaro Fernández-PardoHaemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute of Hospital La Fe, Fernando Abril Martorell 106, 46026, Valencia, Spain.
Francisco EspañaHaemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute of Hospital La Fe, Fernando Abril Martorell 106, 46026, Valencia, Spain.
Manuel Martínez-SarmientoDepartment of Urology, La Fe Hospital, Fernando Abril Martorell 106, 46026, Valencia, Spain.
César D Vera-DonosoDepartment of Urology, La Fe Hospital, Fernando Abril Martorell 106, 46026, Valencia, Spain.
Silvia NavarroHaemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute of Hospital La Fe, Fernando Abril Martorell 106, 46026, Valencia, Spain.
Pilar MedinaHaemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute of Hospital La Fe, Fernando Abril Martorell 106, 46026, Valencia, Spain. medina_pil@gva.es.
Instituto de Investigación Sanitaria La Fe · ESHospital de Cruces · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewRenal cell carcinoma (RCC) is the third most common urologic malignancy. First symptoms are usually unspecific and belated causing the stages to be high when diagnosed. As compensation, incidental detection of RCC by abdominal imaging techniques for other medical purposes is a reality that favours a decrease in the stage of new diagnosed tumours. Therefore, identifying novel predictive biomarkers for diagnosis, progression and prognosis of RCC is fundamental. RECENT

findingsTo date, several studies have demonstrated that microRNAs (miRNAs) play a role in the particular scenario of urologic tumors, and alterations at miRNA level are involved in the initiation, progression and metastases formation of renal cancer. In the present review, we have summarized the up‑to‑date preliminary clinical works on the role of urinary miRNA profiling in RCC, including an evaluation of its value as a potential biomarker for diagnosis, prognosis and follow up of RCC patients.

Indexed as

Biomarkers, TumorCarcinoma, Renal CellDisease ProgressionHumansKidney NeoplasmsMicroRNAsPrognosisBiomarkers, TumorMicroRNAsKidney diseasemicroRNAsRenal cell carcinomaUrologic malignancy

Identifiers

PMID32166474
OpenAlexW3011339409

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.