Evidence map›Paper›PMID 32166469›Full record

SynthesisWorld journal of surgery2020

A Systematic Review and Network-Meta-Analysis of Gastro-Enteric Reconstruction Techniques Following Pancreatoduodenectomy to Reduce Delayed Gastric Emptying.

Sivesh K Kamarajah, James R Bundred, Giorgio Alessandri, Stuart M Robinson, Colin H Wilson, Jeremy J French, Sanjay Pandanaboyana

Abstract readSystematic ReviewNetwork Meta-Analysis
PubMed Publisher
In one paragraph

Synthesis in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sivesh K KamarajahDepartment of Hepatobiliary, Pancreatic and Transplant Surgery, The Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, UK.
James R BundredCollege of Medical and Dental Sciences, University of Birmingham,, Birmingham, UK.
Giorgio AlessandriDepartment of Hepatobiliary, Pancreatic and Transplant Surgery, The Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, UK.
Stuart M RobinsonDepartment of Hepatobiliary, Pancreatic and Transplant Surgery, The Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, UK.
Colin H WilsonDepartment of Hepatobiliary, Pancreatic and Transplant Surgery, The Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, UK.
Jeremy J FrenchDepartment of Hepatobiliary, Pancreatic and Transplant Surgery, The Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, UK.
Sanjay PandanaboyanaDepartment of Hepatobiliary, Pancreatic and Transplant Surgery, The Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, UK. s.pandanaboyana@nhs.net.
Freeman Hospital · GBNewcastle University · GBUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis network meta-analysis aimed to identify the reconstruction technique associated with lowest rates of DGE following pancreatoduodenectomy (PD) from randomised controlled trials (RCTs).

methodsA systematic literature search of PubMed, Embase and MEDLINE databases was carried out using the PRISMA framework to identify all RCTs comparing reconstruction techniques of gastrojejunostomy after PD, with overall DGE as the primary endpoint. The primary outcome measure was overall DGE. Secondary outcomes were grade B/C DGE, duration of nasogastric tube, time to solid food intake, overall and grade B/C pancreatic fistula, bile leaks, reoperation, length of hospital stay and in-hospital mortality.

resultsThe search strategy identified eight RCTs including 761 patients. Six RCTs compared antecolic (n = 291 patients) and retrocolic Billroth II (n = 289 patients) reconstruction (n = 6 studies), and two RCTs compared antecolic Billroth II (n = 92 patients) and Roux-en-Y (n = 89 patients) reconstruction. Overall, antecolic Billroth II ranked best for overall and grade B/C DGE, bile leak, surgical site infection, length of stay and in-hospital mortality. Roux-en-Y was best for overall and grade B/C pancreatic fistula.

conclusionAntecolic Billroth II gastroenteric reconstruction is associated with the lowest rates of delayed gastric emptying after PD amongst the currently available techniques of gastrojejunostomy reconstructions.

Indexed as

PancreaticoduodenectomyGastric BypassGastroenterostomyGastroparesisHumansLength of StayPostoperative ComplicationsRandomized Controlled Trials as TopicReoperationTreatment Outcome

Identifiers

PMID32166469
OpenAlexW3010696193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.