Evidence map›Paper›PMID 32166454›Full record

ReviewCurrent hypertension reports2020

Sleep Disordered Breathing, a Novel, Modifiable Risk Factor for Hypertensive Disorders of Pregnancy.

Laura Sanapo, Margaret H Bublitz, Ghada Bourjeily

Open access · greenAbstract readReview
In one paragraph

Review in Current hypertension reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Timing is everything: snoring onset and blood pressure trajectories in pregnancy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Laura SanapoWomen's Medicine Collaborative-Division of Research, The Miriam Hospital, Providence, RI, USA.
Margaret H BublitzWomen's Medicine Collaborative-Division of Research, The Miriam Hospital, Providence, RI, USA.
Ghada BourjeilyWomen's Medicine Collaborative-Division of Research, The Miriam Hospital, Providence, RI, USA. ghada_bourjeily@brown.edu.ORCID 0000-0002-0543-4719
Providence College · US

Funding

Uncoupling of IL-1 beta and VEGF-A Crosstalk Contributes to Impaired Arteriogenesis Response to Ischemia in Chronic Diabetes MellitusP20GM103652 · NIGMS · OCEAN STATE RESEARCH INSTITUTE, INC. · PI CHOUDHARY, GAURAV, HARRINGTON, ELIZABETH O · 2013 to 2022
$21.3M
Placental role in mediating adverse outcomes in obstructive sleep apneaR01HD078515 · NICHD · MIRIAM HOSPITAL · PI BOURJEILY, GHADA · 2014 to 2018
$2.7M
Predictors of de novo development of obstructive sleep apnea in pregnancyR01HL130702 · NHLBI · MIRIAM HOSPITAL · PI BOURJEILY, GHADA · 2016 to 2020
$2.6M
NHLBI NIH HHS R01 HL130702NICHD NIH HHS R01 HD078515NIGMS NIH HHS P20 GM103652
6 · The paper itself

Abstract

purpose of reviewPathophysiology of hypertensive disorders of pregnancy (HDP), especially preeclampsia, has not been fully elucidated. Most trials aimed at the prevention of preeclampsia have failed to show significant benefit and investigation of novel, modifiable risk factors is sorely needed. Sleep disordered breathing (SDB), a group of disorders for which treatments are available, meets these criteria. SDB impacts about a third of all pregnancies and is associated with hypertension in the general non-pregnant population. RECENT

findingsRecent studies have shown a high prevalence of SDB, especially in complicated pregnancies. Several studies have shown that pregnant women with SDB have a higher risk for developing HDP, and these two disorders are associated with similar maternal long-term cardiovascular outcomes. Based on limited animal models of gestational intermittent hypoxia and human studies, SDB and HDP share similar risk factors and some pathophysiological mechanisms. However, there is paucity of studies addressing causality of this association and identifying therapeutic targets for intervention. Maternal SDB represents a novel and modifiable risk factor of HDP. Further studies are needed in order to establish the exact mechanisms underlying this association and to identify specific areas for clinical interventions.

Indexed as

FemaleHumansHypertension, Pregnancy-InducedPlacentaPolysomnographyPre-EclampsiaPregnancyRisk FactorsSleep Apnea SyndromesHypertensive disorders of pregnancyPlacentaPreeclampsiaPregnancySleep disordered breathing

Identifiers

PMID32166454
PMCPMC8034433
OpenAlexW3012295202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.