Evidence map›Paper›PMID 32166237›Full record

ArticleCritical care explorations2019

Clinical Impact of an Electronic Dashboard and Alert System for Sedation Minimization and Ventilator Liberation: A Before-After Study.

Brian J Anderson, David Do, Corey Chivers, Katherine Choi, Yevgeniy Gitelman, Shivan J Mehta, Venkat Panchandam, Steve Gudowski, Margie Pierce, Maurizio Cereda and 6 more

Abstract read
In one paragraph

Article in Critical care explorations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Investigating Why Clinicians Deviate from Standards of Care: Liberating Patients from Mechanical Ventilation in the ICU.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Brian J AndersonDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA.
David DoDepartment of Neurology, University of Pennsylvania, Philadelphia, PA.
Corey ChiversDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
Katherine ChoiPenn Medicine Center for Health Care Innovation, University of Pennsylvania, Philadelphia, PA.
Yevgeniy GitelmanDepartment of Medicine, University of Pennsylvania, Philadelphia, PA.
Shivan J MehtaDepartment of Medicine, University of Pennsylvania, Philadelphia, PA.
Venkat PanchandamPenn Medicine Penn Value Improvement, University of Pennsylvania, Philadelphia, PA.
Steve GudowskiRespiratory Care Services, University of Pennsylvania, Philadelphia, PA.
Margie PierceRespiratory Care Services, University of Pennsylvania, Philadelphia, PA.
Maurizio CeredaPenn Medicine Predictive Healthcare, University of Pennsylvania, Philadelphia, PA.
Jason D ChristieDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA.
William D SchweickertDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA.
Andrea GabrielliDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA.
Ann HuffenbergerPenn Center for Connected Care, University of Pennsylvania, Philadelphia, PA.
Mike DraugelisDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
Barry D FuchsDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA.

Funding

Mentored Patient Oriented Research in Lung TransplantationK24HL115354 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2012 to 2021
$1.2M
Neurocognitive Impairment in Acute Respiratory Failure and Shock: Understanding the Role of Neuronal ExcitotoxicityK23HL140482 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI ANDERSON, BRIAN J. · 2018 to 2022
$959k
NHLBI NIH HHS K23 HL140482NHLBI NIH HHS K24 HL115354
6 · The paper itself

Abstract

Sedation minimization and ventilator liberation protocols improve outcomes but are challenging to implement. We sought to demonstrate proof-of-concept and impact of an electronic application promoting sedation minimization and ventilator liberation.

designMulti-ICU proof-of-concept study and a single ICU before-after study.

settingUniversity hospital ICUs. PATIENTS: Adult patients receiving mechanical ventilation.

interventionsAn automated application consisting of 1) a web-based dashboard with real-time data on spontaneous breathing trial readiness, sedation depth, sedative infusions, and nudges to wean sedation and ventilatory support and 2) text-message alerts once patients met criteria for a spontaneous breathing trial and spontaneous awakening trial. Pre-intervention, sedation minimization, and ventilator liberation were reviewed daily during a multidisciplinary huddle. Post-intervention, the dashboard was used during the multidisciplinary huddle, throughout the day by respiratory therapists, and text alerts were sent to bedside providers. MEASUREMENTS AND MAIN

resultsWe enrolled 115 subjects in the proof-of-concept study. Spontaneous breathing trial alerts were accurate (98.3%), usually sent while patients were receiving mandatory ventilation (88.5%), and 61.9% of patients received concurrent spontaneous awakening trial alerts. We enrolled 457 subjects in the before-after study, 221 pre-intervention and 236 post-intervention. After implementation, patients were 28% more likely to be extubated (hazard ratio, 1.28; 95% CI, 1.01-1.63;

conclusionsImplementation of an electronic dashboard and alert system promoting sedation minimization and ventilator liberation was associated with reductions in the duration of mechanical ventilation and ICU length of stay.

Indexed as

ABCDEF bundleelectronic dashboardsedation minimizationspontaneous awakening trialspontaneous breathing trial

Identifiers

PMID32166237
PMCPMC7063891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.