Evidence map›Paper›PMID 32166231›Full record

ArticleCritical care explorations2019

Safety of Percutaneous Dilatational Tracheotomy in Patients on Dual Antiplatelet Therapy and Anticoagulation.

Enzo Lüsebrink, Konstantin Stark, Mattis Bertlich, Danny Kupka, Christopher Stremmel, Clemens Scherer, Thomas J Stocker, Mathias Orban, Tobias Petzold, Nikolaus Kneidinger and 3 more

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. [Bone marrow transplantation patients in the intensive care unit].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2021
    Review
  7. Article
  8. Tracheostomy in Adult Intensive Care Unit: An ISCCM Expert Panel Practice Recommendations.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Enzo LüsebrinkIntensive Care Unit, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Konstantin StarkIntensive Care Unit, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Mattis BertlichKlinik und Poliklinik für Hals-Nasen-Ohrenheilkunde, Klinikum der Universität München, Munich, Germany.
Danny KupkaIntensive Care Unit, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Christopher StremmelIntensive Care Unit, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Clemens SchererIntensive Care Unit, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Thomas J StockerIntensive Care Unit, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Mathias OrbanIntensive Care Unit, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Tobias PetzoldIntensive Care Unit, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Nikolaus KneidingerMedizinische Klinik und Poliklinik V, Klinikum der Universität München, Munich, Germany.
Hans-Joachim StemmlerIntensive Care Unit, Medizinische Klinik und Poliklinik III, Klinikum der Universität München, Munich, Germany.
Steffen MassbergIntensive Care Unit, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
Martin OrbanIntensive Care Unit, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany.
German Centre for Cardiovascular Research · DELMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Percutaneous dilatational tracheotomy has become a routine procedure in ICUs. However, given the high and steadily growing number of patients receiving anticoagulation, dual antiplatelet therapy, or even a combination of both (also known as "triple therapy"), there are concerns about the safety of the procedure, in particular for critically ill patients with a high risk of bleeding. In this retrospective study, we investigated whether percutaneous dilatational tracheotomy in this high-risk population was associated with elevated procedural complications.

designRetrospective single-center study with analysis of all percutaneous dilatational tracheotomies performed in our cardiac ICU from January 2018 to May 2019.

settingMunich university hospital's cardiac ICU. PATIENTS AND

interventionsA total of 34 patients who underwent percutaneous dilatational tracheotomy according to Ciaglia technique with accompanying bronchoscopy in our cardiac ICU from January 2018 to May 2019 were included. Patients were stratified into clinically relevant risk groups based on anticoagulation and antiplatelet therapy considering standard laboratory coagulation parameters, that is, activated partial thromboplastin time, international normalized ratio, and platelet count with differentiated analysis of procedure-related complications in each risk group until hospital discharge. MEASUREMENTS AND MAIN

resultsA total of 34 patients who underwent percutaneous dilatational tracheotomy were included and assigned to five clinically relevant treatment groups: IV unfractionated heparin (prophylactic dosage) (

conclusionsBronchoscopy-guided percutaneous dilatational tracheotomy according to Ciaglia technique with careful consideration of all potential indications and contraindications may be a safe and low-complication procedure for airway management, even in patients receiving dual antiplatelet therapy and therapeutic anticoagulation simultaneously in our cohort with a high risk of bleeding.

Indexed as

airway managementanticoagulationantiplatelet therapybleedingpercutaneous dilatational tracheotomy

Identifiers

PMID32166231
PMCPMC7063886
OpenAlexW2979494736

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.