ArticleNetwork neuroscience (Cambridge, Mass.)2020
Organizing principles of whole-brain functional connectivity in zebrafish larvae.
Article in Network neuroscience (Cambridge, Mass.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- The dual interpretation of edge time series: Time-varying connectivity versus statistical interaction.iScience · 2026Article
- Diverging network architecture of theArXiv · 2025Article
- Structural and genetic determinants of zebrafish functional brain networks.Science advances · 2025Article
- Article
- Disentangling the Switching Behavior in Functional Connectivity Dynamics in Autism Spectrum Disorder: Insights from Developmental Cohort Analysis and Molecular-Cellular Associations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Dynamics of specialization in neural modules under resource constraints.Nature communications · 2025Article
- Article
- Two-photon all-optical neurophysiology for the dissection of larval zebrafish brain functional and effective connectivity.Communications biology · 2024Article
- Modular subgraphs in large-scale connectomes underpin spontaneous co-fluctuation events in mouse and human brains.Communications biology · 2024Article
- Living on the edge: network neuroscience beyond nodes.Trends in cognitive sciences · 2023Review
- From single-neuron dynamics to higher-order circuit motifs in control and pathological brain networks.The Journal of physiology · 2023Article
- Microscale Neuronal Activity Collectively Drives Chaotic and Inflexible Dynamics at the Macroscale in Seizures.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- High-amplitude network co-fluctuations linked to variation in hormone concentrations over the menstrual cycle.Network neuroscience (Cambridge, Mass.) · 2023Article
- Toward an integrative neurovascular framework for studying brain networks.Neurophotonics · 2022Article
- Multimodal Characterization of Seizures in Zebrafish Larvae.Biomedicines · 2022Article
- Local structure-function relationships in human brain networks across the lifespan.Nature communications · 2022Article
- Brain-wide visual habituation networks in wild type and fmr1 zebrafish.Nature communications · 2022Article
- From calcium imaging to graph topology.Network neuroscience (Cambridge, Mass.) · 2022Review
- Article
- Sensory-motor cortices shape functional connectivity dynamics in the human brain.Nature communications · 2021Article
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Abstract
Network science has begun to reveal the fundamental principles by which large-scale brain networks are organized, including geometric constraints, a balance between segregative and integrative features, and functionally flexible brain areas. However, it remains unknown whether whole-brain networks imaged at the cellular level are organized according to similar principles. Here, we analyze whole-brain functional networks reconstructed from calcium imaging data recorded in larval zebrafish. Our analyses reveal that functional connections are distance-dependent and that networks exhibit hierarchical modular structure and hubs that span module boundaries. We go on to show that spontaneous network structure places constraints on stimulus-evoked reconfigurations of connections and that networks are highly consistent across individuals. Our analyses reveal basic organizing principles of whole-brain functional brain networks at the mesoscale. Our overarching methodological framework provides a blueprint for studying correlated activity at the cellular level using a low-dimensional network representation. Our work forms a conceptual bridge between macro- and mesoscale network neuroscience and opens myriad paths for future studies to investigate network structure of nervous systems at the cellular level.
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