Evidence map›Paper›PMID 32166121›Full record

ArticleClinical and experimental hepatology2020

Mac-2 binding protein in non-alcoholic fatty liver disease: Is it a reliable diagnostic biomarker? A pilot study.

Rokaya Abd El-Aziz, Alshaimaa Rezk L R Alnaggar, Mona Ibrahim Mohamed Nabih, Shaimaa Mohammed Ali, Hany Khattab, Sahar Abd El-Atty

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rokaya Abd El-AzizInternal Medicine Department, Kasr Alainy Hospital, Faculty of Medicine, Cairo University, Egypt.
Alshaimaa Rezk L R AlnaggarInternal Medicine Department, Kasr Alainy Hospital, Faculty of Medicine, Cairo University, Egypt.
Mona Ibrahim Mohamed NabihInternal Medicine Department, Kasr Alainy Hospital, Faculty of Medicine, Cairo University, Egypt.
Shaimaa Mohammed AliInternal Medicine Department, Kasr Alainy Hospital, Faculty of Medicine, Cairo University, Egypt.
Hany KhattabPathology Department, Kasr Alainy Hospital, Faculty of Medicine, Cairo University, Egypt.
Sahar Abd El-AttyClinical and Chemical Pathology Department, Kasr Alainy Hospital, Faculty of Medicine, Cairo University, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aim of the studyThis study aimed to assess the level of serum Mac-2 binding protein (Mac-2BP) as a non-invasive biomarker for the diagnosis of non-alcoholic fatty liver disease (NAFLD). MATERIAL AND

methodsForty patients with NAFLD and 15 healthy sex- and age-matched subjects were included in this pilot study. Serum Mac-2BP level was measured using ELISA. Liver biopsy was taken from 20 patients.

resultsThere was no statistically significant difference between patients and controls regarding the level of Mac-2BP (

conclusionsThis study showed that Mac-2BP is not elevated in NAFLD patients compared to controls. It also demonstrated that the reliability of Mac-2BP as a biomarker for NAFLD diagnosis is still controversial and needs more investigation.

Indexed as

biomarkerMac-2BPnon-alcoholic fatty liver diseasenon-alcoholic steatohepatitis

Identifiers

PMID32166121
PMCPMC7062116
OpenAlexW3007706446

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.