Evidence map›Paper›PMID 32166115›Full record

ArticleScience advances2020

Learning to learn from data: Using deep adversarial learning to construct optimal statistical procedures.

Alex Luedtke, Marco Carone, Noah Simon, Oleg Sofrygin

Abstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Adversarial Monte Carlo Meta-Learning of Optimal Prediction Procedures.Journal of machine learning research : JMLR · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alex LuedtkeDepartment of Statistics, University of Washington, Box 354322, Seattle, WA 98195, USA.ORCID 0000-0002-9936-3236
Marco CaroneVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Mail Stop E5-110, Seattle, WA 98109, USA.ORCID 0000-0003-2106-0953
Noah SimonDepartment of Biostatistics, University of Washington, Box 357232, Seattle, WA 98195, USA.
Oleg SofryginDivision of Research, Kaiser Permanente, 2000 Broadway, Oakland, CA 94612, USA.ORCID 0000-0002-9539-8853

Funding

SDMC: HIV Vaccine Trials NetworkUM1AI068635 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Peter B. Gilbert, Yunda Huang · 2011 to 2026
$385.9M
Data-Driven Statistical Learning with Applications to GenomicsDP5OD019820 · OD · UNIVERSITY OF WASHINGTON · PI SIMON, NOAH · 2014 to 2018
$1.7M
NIAID NIH HHS UM1 AI068635NIH HHS DP5 OD019820
6 · The paper itself

Abstract

Traditionally, statistical procedures have been derived via analytic calculations whose validity often relies on sample size growing to infinity. We use tools from deep learning to develop a new approach, adversarial Monte Carlo meta-learning, for constructing optimal statistical procedures. Statistical problems are framed as two-player games in which Nature adversarially selects a distribution that makes it difficult for a statistician to answer the scientific question using data drawn from this distribution. The players' strategies are parameterized via neural networks, and optimal play is learned by modifying the network weights over many repetitions of the game. Given sufficient computing time, the statistician's strategy is (nearly) optimal at the finite observed sample size, rather than in the hypothetical scenario where sample size grows to infinity. In numerical experiments and data examples, this approach performs favorably compared to standard practice in point estimation, individual-level predictions, and interval estimation.

Identifiers

PMID32166115
PMCPMC7051830

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.