ReviewSAGE open medicine2020
What are the association patterns between handgrip strength and adverse health conditions? A topical review.
Review in SAGE open medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Factors associated with handgrip strength across the life course: A systematic review.Journal of cachexia, sarcopenia and muscle · 2024Pooled it
- Hand Grip Force-Time Curve Indicators Evaluated by Dynamometer: A Systematic Review.Nutrients · 2024Pooled it
- The predictive value of masticatory function for adverse health outcomes in older adults: a systematic review.The journal of nutrition, health & aging · 2024Pooled it
- Effect of isometric handgrip exercise on cognitive function: Current evidence, methodology, and safety considerations.Frontiers in physiology · 2022Pooled it
- Unilateral Balance, Muscular Strength, Foot Arch Status, and Physical Performance in Young Adults with and Without Low Back Pain.Journal of clinical medicine · 2026Article
- Foot Arch Status and Muscular Strength: Associations with Unilateral Balance and Physical Performance.Diagnostics (Basel, Switzerland) · 2026Article
- Empathy in Public Safety: Selection Standards, Gender Differences, and Relations with Existing Selection Predictors.Journal of functional morphology and kinesiology · 2026Article
- Handgrip and gait metrics as scalable markers of physical health in schizophrenia and alcohol use disorders.Global mental health (Cambridge, England) · 2026Article
- Rethinking Low Handgrip Strength: Normative Values, Diagnostic Thresholds, and Sarcopenia Risk in Malaysian Older Adults.Clinical interventions in aging · 2026Article
- The relationship between grip strength, 6 minute walking distance and working memory in older adults with mild cognitive impairment: an fNIRS study.BMC geriatrics · 2025Article
- The Effects of Time-Restricted Feeding on Handgrip Strength, Vigilance, and Perceived Anxiety and Depression in Older Adults: A Comparative Study Between Active and Sedentary Populations.Health science reports · 2025Article
- Impact of Hydroxy-Methyl-Butyrate Supplementation on Malnourished Patients Assessed Using AI-Enhanced Ultrasound Imaging.Journal of cachexia, sarcopenia and muscle · 2025Article
- Relationship between handgrip strength and timed up-and-go test on hospitalization costs in older adults: a population-based study.BMC public health · 2025Article
- Can handgrip strength alone detect individuals living with frailty according to the Clinical Frailty Scale?Revista da Associacao Medica Brasileira (1992) · 2025Article
- Observing the Relationship Between Additional Measures of Handgrip Strength and the 6-Minute Push Test in Ambulatory Young Adults.International journal of exercise science · 2025Article
- The usefulness of a body shape index in assessing muscle function and strength in older adults hemodialysis patients.Frontiers in endocrinology · 2025Article
- Predictive models of weakness among older adults: the contribution of oral health indicators.Brazilian oral research · 2025Article
- Development and cross-validation of LMS-based normative reference standards and health benefits zones for muscular strength among adolescents by age and sex.Frontiers in public health · 2025Article
- Preoperative muscle function assessments in nursing as predictors of postoperative outcomes in patients with colorectal cancer and malnutrition.Frontiers in nutrition · 2025Article
- Factors Affecting Handgrip Strength in Menopausal Women at High Risk of Sarcopenia: A National Population-Based Study.Healthcare (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Measures of handgrip strength can be used to conveniently assess overall muscle strength capacity. Although stand-alone measures of handgrip strength provide robust health information, the clinical meaningfulness to determine prevention and treatment options for weakness remains limited because the etiology of muscle weakness remains unclear. Moreover, clinical outcomes associated with handgrip strength are wide-ranging. Therefore, disentangling how handgrip strength is associated with health conditions that are metabolically or neurologically driven may improve our understanding of the factors linked to handgrip strength. The purpose of this topical review was to highlight and summarize evidence examining the associations of handgrip strength with certain health outcomes that are metabolically and neurologically driven. From this perusal of the literature, we posit that stand-alone handgrip strength be considered an umbrella assessment of the body systems that contribute to strength capacity, and a panoptic measurement of muscle strength that is representative of overall health status, not a specific health condition. Recommendations for future strength capacity-related research are also provided.
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