Evidence map›Paper›PMID 32165915›Full record

ArticleInfectious agents and cancer2020

Human papillomavirus (HPV) 16 infection is not detected in rectal carcinoma.

Sandra F Martins, Vânia Mariano, Mesquita Rodrigues, Adhemar Longatto-Filho

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infectious agents and cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Sandra F Martins *1Life and Health Science Research Institute (ICVS), School of Health Sciences, School of Medicine, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Vânia Mariano *Molecular Oncology Research Center, Barretos, São Paulo, Brazil.
Mesquita RodriguesColoproctology Unit, Braga Hospital, Braga, Portugal.
Adhemar Longatto-Filho1Life and Health Science Research Institute (ICVS), School of Health Sciences, School of Medicine, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-5779-9752
Hospital Braga · PTHospital de Câncer de Barretos · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPersistence of human papillomavirus (HPV) infections is associated with squamous cell carcinomas of different human anatomic sites. Several studies have suggested a potential role for HPV infection, particularly HPV16 genotype, in rectal cancer carcinogenesis.. The aim of this study was to assess the frequency of oncogenic HPV 16 viral DNA sequences in rectal carcinomas cases retrieved from the pathology archive of Braga Hospital, North Portuga.

methodsTaqMan-based type-specific real-time PCR for HPV 16 was performed using primers and probe targeting HPV16 E7 region.

resultsMost of the rectal cancer patients (88.5%,

conclusionThe total of negative tests for HPV 16 infection is a robust argument to support the assumption that HPV 16 infection, despite of previous evidences, is not involved in rectal cancer carcinogenesis and progression.

Indexed as

CarcinogenesisHuman papillomavirus 16Rectal cancer

Identifiers

PMID32165915
PMCPMC7059378
OpenAlexW3011627077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.