ArticleNeuro-ophthalmology (Aeolus Press)2019
Ganglion Cell Topography Indicates Pre- or Postnatal Damage to the Retro-Geniculate Visual System, Predicts Visual Field Function and May Identify Cerebral Visual Impairment in Children - A Multiple Case Study.
Article in Neuro-ophthalmology (Aeolus Press), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Clinical assessment, investigation, diagnosis and initial management of cerebral visual impairment: a consensus practice guide.Eye (London, England) · 2023Guideline
- The NR2F1-Related 5q14.3-q21.1 deletion causing periventricular heterotopia with cerebral visual impairment: a longitudinal case report and genotype-phenotype analysis.Frontiers in genetics · 2026Article
- Natural history of cerebral visual impairment in children with cerebral palsy.Developmental medicine and child neurology · 2025Article
- Cerebral versus cortical visual impairment: eliminating the conflict and renewing the terminology.BMC ophthalmology · 2024Article
- Childhood cerebral visual impairment subtype classification based on an extensive versus a limited test battery.Frontiers in neuroscience · 2023Article
- Lateral Geniculate Nucleus Volume Determined on MRI Correlates With Corresponding Ganglion Cell Layer Loss in Acquired Human Postgeniculate Lesions.Investigative ophthalmology & visual science · 2022Article
- Article
- The Multidisciplinary Guidelines for Diagnosis and Referral in Cerebral Visual Impairment.Frontiers in human neuroscience · 2022Article
- Periventricular leukomalacia: an ophthalmic perspective.Medical journal, Armed Forces India · 2021Review
- Pre- and Postnatal Damage to the Retro-Geniculate Visual Pathways Cause Retinal Degeneration Predictive for Visual Function.Frontiers in human neuroscience · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this paper, we quantify the degree of ganglion cell layer thinning due to retrograde trans-synaptic degeneration (RTSD) from retro-geniculate damage in six cases who had homonymous visual field defects known since childhood. Three had prenatal injuries, occurring close to mid-gestation and in the first parts of the early and late third trimester, respectively, and representing injuries at different early developmental stages. Three had later acquired injuries, at age 1.5, 4 and 13 years. The impact of the injury to the optic radiations was revealed by fibre tractography. The ganglion cell thinning corresponded with the visual field defects and the extent and location of the primary brain damage. The most important sign of RTSD was asymmetry of the ganglion cell topography within the macular area.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.