Evidence map›Paper›PMID 32165862›Full record

ReviewCancer cell international2020

The clinical prognostic value of lncRNA FAM83H-AS1 in cancer patients: a meta-analysis.

Qin Yang, Jie Wang, Pingyong Zhong, Tinggang Mou, Hao Hua, Pan Liu, Fei Xie

Open access · goldAbstract readReview
In one paragraph

Review in Cancer cell international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qin Yang *Department of Gastroenterology, The First People's Hospital of Neijiang, Neijiang, Sichuan China.
Jie Wang *Department of Hepatic-Biliary-Pancreatic Surgery, The First People's Hospital of Neijiang, No. 31, Tuozhong Lane, Jiaotong Road, Neijiang, 641000 Sichuan China.ORCID 0000-0002-7096-9939
Pingyong ZhongDepartment of Hepatic-Biliary-Pancreatic Surgery, The First People's Hospital of Neijiang, No. 31, Tuozhong Lane, Jiaotong Road, Neijiang, 641000 Sichuan China.
Tinggang MouDepartment of Hepatic-Biliary-Pancreatic Surgery, The First People's Hospital of Neijiang, No. 31, Tuozhong Lane, Jiaotong Road, Neijiang, 641000 Sichuan China.
Hao HuaDepartment of Hepatic-Biliary-Pancreatic Surgery, The First People's Hospital of Neijiang, No. 31, Tuozhong Lane, Jiaotong Road, Neijiang, 641000 Sichuan China.
Pan LiuDepartment of Hepatic-Biliary-Pancreatic Surgery, The First People's Hospital of Neijiang, No. 31, Tuozhong Lane, Jiaotong Road, Neijiang, 641000 Sichuan China.
Fei XieDepartment of Hepatic-Biliary-Pancreatic Surgery, The First People's Hospital of Neijiang, No. 31, Tuozhong Lane, Jiaotong Road, Neijiang, 641000 Sichuan China.
Neijiang Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFamily with sequence similarity 83 member H antisense RNA 1 (FAM83H-AS1) is a novel long non-coding RNA. Increasing studies have reported that FAM83H-AS1 is abnormally expressed in a variety of tumors and is associated with poor outcome. However, the clinical prognostic significance of lncRNA FAM83H-AS1 in tumors is not completely known.

methodsIn this meta-analysis, literature was collected up until February 5, 2020 through multifarious retrieval strategies by searching through electronic databases of PubMed, Cochrane Library, EMBASE, Medline, Web of Science, CNKI, Weipu, and Wanfang. A total of 14 studies that met the inclusion criteria with relevant clinical data and prognostic information were included in the meta-analysis.

resultsThe combined results revealed that high expression of FAM83H-AS1 was associated with poor overall survival (OS) (HR = 1.63, 95% CI 1.24-2.14,

conclusionsOur results of this meta-analysis indicated that elevated FAM83H-AS1 expression could predict poor prognosis in patients with cancer and suggested that FAM83H-AS1 might serve as a novel biomarker for cancer.

Indexed as

CancerFAM83H-AS1Long non-coding RNAOverall survivalPrognosis

Identifiers

PMID32165862
PMCPMC7059312
OpenAlexW3011588561

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.