Evidence map›Paper›PMID 32165585›Full record

ArticleScience (New York, N.Y.)2020

Structure of V-ATPase from the mammalian brain.

Yazan M Abbas, Di Wu, Stephanie A Bueler, Carol V Robinson, John L Rubinstein

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 244 citations in OpenAlex.

  1. Article
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  4. Article
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  8. Article
  9. Review
  10. Article
  11. Article
  12. The V-ATPase VJournal of oral microbiology · 2026
    Article
  13. Article
  14. Review
  15. [Effect of dephosphorylation of tumor metastasis suppressor geneBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Article
  16. Article
  17. Cryo-EM single-particle analysis expanding towards increasingly native samples.Acta crystallographica. Section D, Structural biology · 2025
    Review
  18. Article
  19. RNAi ofInsects · 2025
    Article
  20. Article

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Yazan M AbbasMolecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada.ORCID 0000-0001-5625-1034
Di WuPhysical and Theoretical Chemistry Laboratory, University of Oxford, Oxford OX1 3QZ, UK.
Stephanie A BuelerMolecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada.
Carol V RobinsonPhysical and Theoretical Chemistry Laboratory, University of Oxford, Oxford OX1 3QZ, UK.ORCID 0000-0001-7829-5505
John L RubinsteinMolecular Medicine Program, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada. john.rubinstein@utoronto.ca.ORCID 0000-0003-0566-2209
Hospital for Sick Children · CAUniversity of Oxford · GBUniversity of Toronto · CA

Funding

CIHREuropean Research Council 695511Wellcome Trust 104633
6 · The paper itself

Abstract

In neurons, the loading of neurotransmitters into synaptic vesicles uses energy from proton-pumping vesicular- or vacuolar-type adenosine triphosphatases (V-ATPases). These membrane protein complexes possess numerous subunit isoforms, which complicates their analysis. We isolated homogeneous rat brain V-ATPase through its interaction with SidK, a

Indexed as

AnimalsBacterial ProteinsBiocatalysisBiomarkersBrainCell MembraneCryoelectron MicroscopyModels, ChemicalProrenin ReceptorProtein DomainsRatsReceptors, Cell SurfaceRenin-Angiotensin SystemVacuolar Proton-Translocating ATPasesWnt Signaling PathwayAtp6ap1 protein, ratATP6AP2 protein, ratBacterial ProteinsBiomarkersProrenin ReceptorReceptors, Cell SurfaceVacuolar Proton-Translocating ATPases

Identifiers

PMID32165585
PMCPMC7324285
OpenAlexW3012090331

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.