Evidence map›Paper›PMID 32165492›Full record

ArticleDevelopment (Cambridge, England)2020

Role of nutrient-driven O-GlcNAc-post-translational modification in pancreatic exocrine and endocrine islet development.

Daniel Baumann, Alicia Wong, Brian Akhaphong, Seokwon Jo, Samantha Pritchard, Ramkumar Mohan, Grace Chung, Ying Zhang, Emilyn U Alejandro

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Metabolites · 2022
    Review
  9. Article
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  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Daniel BaumannDepartment of Integrative Biology and Physiology, University of Minnesota Medical School. Minneapolis, MN 55455, USA.
Alicia WongDepartment of Integrative Biology and Physiology, University of Minnesota Medical School. Minneapolis, MN 55455, USA.
Brian AkhaphongDepartment of Integrative Biology and Physiology, University of Minnesota Medical School. Minneapolis, MN 55455, USA.
Seokwon JoDepartment of Integrative Biology and Physiology, University of Minnesota Medical School. Minneapolis, MN 55455, USA.
Samantha PritchardDepartment of Integrative Biology and Physiology, University of Minnesota Medical School. Minneapolis, MN 55455, USA.
Ramkumar MohanDepartment of Integrative Biology and Physiology, University of Minnesota Medical School. Minneapolis, MN 55455, USA.
Grace ChungDepartment of Integrative Biology and Physiology, University of Minnesota Medical School. Minneapolis, MN 55455, USA.
Ying ZhangMinnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN 55455, USA.
Emilyn U AlejandroDepartment of Integrative Biology and Physiology, University of Minnesota Medical School. Minneapolis, MN 55455, USA ealejand@umn.edu.ORCID 0000-0002-7941-8439
University of Minnesota Medical Center · USUniversity of Minnesota · US

Funding

Minnesota Obesity Prevention Training (MnOPT)T32DK083250 · NIDDK · UNIVERSITY OF MINNESOTA · PI KOTZ, CATHERINE M, LASKA, MELISSA N. · 2010 to 2024
$5.1M
TRAINING GRANT IN DIABETES, ENDOCRINOLOGY, &METABOLISMT32DK007203 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI LISA Senye CHOW, Douglas G Mashek · 1986 to 2026
$4.3M
The role of O-linked N-Acetylglucosamine Homeostasis in Pancreatic Beta-cell Development and FunctionR01DK115720 · NIDDK · UNIVERSITY OF MINNESOTA · PI ALEJANDRO, EMILYN · 2018 to 2022
$1.9M
O-linked-N-acetylglucosamine Post-translational Modification in Pancreatic Beta-cells Regulating ER Stress and Mitochondrial FunctionR21DK112144 · NIDDK · UNIVERSITY OF MINNESOTA · PI ALEJANDRO, EMILYN · 2017 to 2019
$576k
Role of placental nutrient-sensor protein mTOR on fetal programming of beta-cell dysfunction and susceptibility to type 2 diabetesR03DK114465 · NIDDK · UNIVERSITY OF MINNESOTA · PI ALEJANDRO, EMILYN · 2018 to 2019
$360k
NIDDK NIH HHS R01 DK115720NIDDK NIH HHS R03 DK114465NIDDK NIH HHS R21 DK112144NIDDK NIH HHS T32 DK007203NIDDK NIH HHS T32 DK083250
6 · The paper itself

Abstract

Although the developing pancreas is exquisitely sensitive to nutrient supply

Indexed as

AcetylglucosamineAnimalsEmbryo, MammalianFemaleIslets of LangerhansMaleMiceMice, Inbred C57BLMice, KnockoutN-AcetylglucosaminyltransferasesNutrientsPancreas, ExocrineProtein Processing, Post-TranslationalSignal TransductionAcetylglucosamineN-AcetylglucosaminyltransferasesNutrientsUDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferaseHexosamine biosynthetic pathwayIslet developmentNutrientsO-GlcNAc TransferaseO-GlcNAcylationPancreas development

Identifiers

PMID32165492
PMCPMC7174839
OpenAlexW3012546323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.